ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesI21.1

I21.1

Non-billable

ST elevation (STEMI) myocardial infarction of inferior wall

BILLABLE STATUSNo
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/06/2025

Code Description

ICD-10 I21.1 is a used to indicate a diagnosis of st elevation (stemi) myocardial infarction of inferior wall.

Key Diagnostic Point:

I21.1 refers to ST elevation myocardial infarction (STEMI) of the inferior wall, a critical cardiovascular condition characterized by the occlusion of the right coronary artery (RCA) or the left circumflex artery (LCx), leading to ischemia and necrosis of the inferior myocardial wall. Clinically, patients may present with chest pain, shortness of breath, diaphoresis, and nausea. The inferior wall is primarily supplied by the RCA in right-dominant coronary systems, and ischemia can lead to complications such as arrhythmias, heart failure, or cardiogenic shock. Diagnosis typically involves an electrocardiogram (ECG) showing ST-segment elevation in leads II, III, and aVF, alongside elevated cardiac biomarkers. The progression of the disease can vary, with timely intervention being crucial to minimize myocardial damage. Treatment often includes reperfusion therapy, such as percutaneous coronary intervention (PCI) or thrombolytics, and subsequent management may involve antiplatelet therapy, beta-blockers, and lifestyle modifications.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Diagnostic complexity: Requires ECG interpretation and biomarker analysis.
  • Treatment complexity: Involves acute intervention and long-term management.
  • Documentation requirements: Detailed clinical notes and treatment plans are essential.
  • Coding specificity: Requires precise identification of myocardial infarction type and location.

Audit Risk Factors

  • Common coding errors: Misidentification of the myocardial wall affected.
  • Documentation gaps: Incomplete clinical notes regarding symptoms and treatment.
  • Billing challenges: Potential denials due to lack of supporting documentation.

Specialty Focus

Medical Specialties

Cardiology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Emergency Medicine

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Related ICD-10 Codes

Related CPT Codes

CPT Code

Clinical Scenario

Documentation Requirements

CPT Code

Clinical Scenario

Documentation Requirements

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The clinical significance of I21.1 is profound, as inferior wall STEMIs can lead to serious complications and increased morbidity and mortality rates. Population health impact includes a high prevalence of coronary artery disease, necessitating effective management strategies. Quality measures focus on timely reperfusion therapy and adherence to guidelines, which can improve outcomes. Understanding healthcare utilization patterns related to STEMIs can help in resource allocation and improving care delivery for affected populations.

ICD-9 vs ICD-10

The clinical significance of I21.1 is profound, as inferior wall STEMIs can lead to serious complications and increased morbidity and mortality rates. Population health impact includes a high prevalence of coronary artery disease, necessitating effective management strategies. Quality measures focus on timely reperfusion therapy and adherence to guidelines, which can improve outcomes. Understanding healthcare utilization patterns related to STEMIs can help in resource allocation and improving care delivery for affected populations.

Reimbursement & Billing Impact

Reimbursement considerations include the need for comprehensive documentation that supports the diagnosis of STEMI, including ECG findings and treatment interventions. Common denials may arise from insufficient documentation or coding errors, particularly in distinguishing between different types of myocardial infarctions. Best practices include ensuring all clinical notes are complete and that the coding accurately reflects the patient's condition and treatment provided.

Resources

Clinical References

  • •
    ICD-10 Official Guidelines for I00-I99
  • •
    Clinical Documentation Requirements

Coding & Billing References

  • •
    ICD-10 Official Guidelines for I00-I99
  • •
    Clinical Documentation Requirements

Frequently Asked Questions

What specific conditions are covered by I21.1?

I21.1 specifically covers ST elevation myocardial infarction affecting the inferior wall of the heart, typically resulting from occlusion of the RCA or LCx. It is characterized by ST-segment elevation in the inferior leads on an ECG and is associated with elevated cardiac enzymes.

When should I21.1 be used instead of related codes?

I21.1 should be used when the clinical presentation and diagnostic findings confirm an inferior wall STEMI, as indicated by specific ECG changes and symptomatology. It is crucial to differentiate it from other types of myocardial infarctions based on the location of the ischemia.

What documentation supports I21.1?

Documentation for I21.1 should include a detailed clinical assessment, ECG findings showing ST elevation in leads II, III, and aVF, and laboratory results indicating elevated cardiac biomarkers. Treatment plans and follow-up notes are also essential.