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ICD-10 Guide
ICD-10 CodesI25.110

I25.110

Billable

Atherosclerotic heart disease of native coronary artery with unstable angina pectoris

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/06/2025

Code Description

ICD-10 I25.110 is a billable code used to indicate a diagnosis of atherosclerotic heart disease of native coronary artery with unstable angina pectoris.

Key Diagnostic Point:

I25.110 refers to atherosclerotic heart disease of the native coronary artery accompanied by unstable angina pectoris. This condition is characterized by the narrowing or blockage of coronary arteries due to atherosclerosis, which is the buildup of plaques made up of fat, cholesterol, and other substances. The clinical presentation often includes episodes of chest pain or discomfort that may occur at rest or with minimal exertion, indicating a significant risk of myocardial infarction. The anatomy involved primarily includes the coronary arteries, which supply blood to the heart muscle. Disease progression can lead to chronic ischemic heart disease and potentially result in acute coronary syndromes. Diagnostic considerations include a thorough patient history, physical examination, electrocardiograms (ECGs), and imaging studies such as stress tests or coronary angiography to assess the severity of arterial blockages and the presence of ischemia.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Diagnostic complexity: Requires comprehensive assessment of symptoms and risk factors.
  • Treatment complexity: May involve medication management, lifestyle changes, and possibly invasive procedures.
  • Documentation requirements: Detailed clinical documentation is essential to support the diagnosis.
  • Coding specificity: Requires precise coding to differentiate from other types of heart disease.

Audit Risk Factors

  • Common coding errors: Misclassification of stable vs. unstable angina.
  • Documentation gaps: Incomplete clinical notes regarding symptoms and treatment.
  • Billing challenges: Potential denials if documentation does not clearly support the diagnosis.

Specialty Focus

Medical Specialties

Cardiology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Internal Medicine

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Related ICD-10 Codes

Related CPT Codes

CPT Code

Clinical Scenario

Documentation Requirements

CPT Code

Clinical Scenario

Documentation Requirements

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The clinical significance of I25.110 lies in its association with increased morbidity and mortality due to potential heart attacks. This condition affects a substantial portion of the population, particularly older adults and those with risk factors such as hypertension, diabetes, and hyperlipidemia. Understanding and accurately coding this condition is crucial for quality measures and population health management, as it influences healthcare utilization patterns and resource allocation in cardiovascular care.

ICD-9 vs ICD-10

The clinical significance of I25.110 lies in its association with increased morbidity and mortality due to potential heart attacks. This condition affects a substantial portion of the population, particularly older adults and those with risk factors such as hypertension, diabetes, and hyperlipidemia. Understanding and accurately coding this condition is crucial for quality measures and population health management, as it influences healthcare utilization patterns and resource allocation in cardiovascular care.

Reimbursement & Billing Impact

reimbursement considerations and to ensure compliance with coding best practices to minimize audit risks.

Resources

Clinical References

  • •
    ICD-10 Official Guidelines for I00-I99
  • •
    Clinical Documentation Requirements

Coding & Billing References

  • •
    ICD-10 Official Guidelines for I00-I99
  • •
    Clinical Documentation Requirements

Frequently Asked Questions

What specific conditions are covered by I25.110?

I25.110 covers atherosclerotic heart disease of the native coronary artery specifically associated with unstable angina pectoris. This includes patients experiencing chest pain that is unpredictable and may occur at rest, indicating a higher risk for acute coronary events.

When should I25.110 be used instead of related codes?

I25.110 should be used when a patient presents with unstable angina pectoris due to atherosclerotic changes in the coronary arteries. It is important to differentiate this from stable angina (I25.109) or other forms of heart disease to ensure accurate treatment and management.

What documentation supports I25.110?

Documentation for I25.110 should include a detailed patient history of angina symptoms, results from diagnostic tests such as ECGs or stress tests, and any imaging studies that confirm the presence of atherosclerosis in the coronary arteries. Clinical notes must clearly indicate the unstable nature of the angina.