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ICD-10 Guide
ICD-10 CodesI25.750

I25.750

Billable

Atherosclerosis of native coronary artery of transplanted heart with unstable angina

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/06/2025

Code Description

ICD-10 I25.750 is a billable code used to indicate a diagnosis of atherosclerosis of native coronary artery of transplanted heart with unstable angina.

Key Diagnostic Point:

I25.750 refers to atherosclerosis of the native coronary artery of a transplanted heart, presenting with unstable angina. This condition arises when the transplanted heart's native coronary arteries develop atherosclerotic plaques, leading to reduced blood flow and oxygen supply to the heart muscle. Clinically, patients may experience episodes of chest pain, shortness of breath, or other symptoms indicative of myocardial ischemia. The anatomy involved includes the coronary arteries that supply blood to the heart muscle, which can become narrowed or blocked due to plaque buildup. Disease progression can lead to acute coronary syndromes, including unstable angina, which is characterized by increased frequency, duration, or intensity of angina symptoms. Diagnostic considerations include a thorough clinical evaluation, electrocardiogram (ECG), stress testing, and imaging studies such as coronary angiography to assess the severity of coronary artery disease. Management may involve lifestyle modifications, pharmacotherapy, and potentially revascularization procedures depending on the severity of the condition.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Diagnostic complexity: Requires comprehensive evaluation of cardiac symptoms and history of heart transplantation.
  • Treatment complexity: May involve multiple treatment modalities including medications and surgical interventions.
  • Documentation requirements: Detailed clinical documentation is necessary to justify the diagnosis and treatment plan.
  • Coding specificity: Requires precise coding to differentiate from other forms of coronary artery disease.

Audit Risk Factors

  • Common coding errors: Misclassification of stable vs. unstable angina.
  • Documentation gaps: Incomplete clinical notes regarding the patient's history and symptoms.
  • Billing challenges: Potential denials if documentation does not clearly support the diagnosis.

Specialty Focus

Medical Specialties

Cardiology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Transplant Medicine

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Related ICD-10 Codes

Related CPT Codes

CPT Code

Clinical Scenario

Documentation Requirements

CPT Code

Clinical Scenario

Documentation Requirements

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The clinical significance of I25.750 lies in its association with increased morbidity and mortality in heart transplant recipients. Unstable angina can lead to acute coronary syndromes, necessitating urgent medical intervention. Understanding the epidemiology of this condition is crucial for population health, as it highlights the need for ongoing monitoring and management of cardiovascular health in transplant patients. Quality measures should focus on early detection and treatment to improve outcomes and reduce healthcare utilization.

ICD-9 vs ICD-10

The clinical significance of I25.750 lies in its association with increased morbidity and mortality in heart transplant recipients. Unstable angina can lead to acute coronary syndromes, necessitating urgent medical intervention. Understanding the epidemiology of this condition is crucial for population health, as it highlights the need for ongoing monitoring and management of cardiovascular health in transplant patients. Quality measures should focus on early detection and treatment to improve outcomes and reduce healthcare utilization.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    ICD-10 Official Guidelines for I00-I99
  • •
    Clinical Documentation Requirements

Coding & Billing References

  • •
    ICD-10 Official Guidelines for I00-I99
  • •
    Clinical Documentation Requirements

Frequently Asked Questions

What specific conditions are covered by I25.750?

I25.750 covers atherosclerosis of the native coronary artery of a transplanted heart specifically when the patient presents with unstable angina. This includes symptoms such as chest pain at rest, increased frequency of angina episodes, or angina that is more severe than previously experienced.

When should I25.750 be used instead of related codes?

I25.750 should be used when the patient exhibits unstable angina related to atherosclerosis of the native coronary artery in a transplanted heart. It is important to differentiate this from stable angina (I25.751) or other forms of coronary artery disease to ensure accurate coding and appropriate treatment.

What documentation supports I25.750?

Documentation should include a detailed history of the patient's heart transplant, current symptoms of unstable angina, results from diagnostic tests such as ECG or angiography, and any treatment plans or interventions that have been initiated.