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ICD-10 Guide
ICD-10 CodesI45.6

I45.6

Billable

Pre-excitation syndrome

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/06/2025

Code Description

ICD-10 I45.6 is a billable code used to indicate a diagnosis of pre-excitation syndrome.

Key Diagnostic Point:

Pre-excitation syndrome, commonly associated with conditions such as Wolff-Parkinson-White (WPW) syndrome, is characterized by the presence of an accessory conduction pathway that allows electrical impulses to bypass the normal route through the atrioventricular (AV) node. This results in a premature activation of the ventricles, leading to episodes of tachycardia. Clinically, patients may present with palpitations, dizziness, syncope, or even sudden cardiac arrest in severe cases. The anatomy involved primarily includes the heart's conduction system, particularly the atria, ventricles, and the accessory pathways. Disease progression can vary; some individuals may remain asymptomatic, while others may experience recurrent arrhythmias that necessitate intervention. Diagnostic considerations include electrocardiograms (ECGs) that reveal characteristic findings such as a shortened PR interval and a delta wave. Electrophysiological studies may also be employed to confirm the diagnosis and assess the risk of arrhythmias. Understanding the clinical presentation and potential complications is essential for effective management and treatment planning.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Diagnostic complexity
  • Treatment complexity
  • Documentation requirements
  • Coding specificity

Audit Risk Factors

  • Common coding errors
  • Documentation gaps
  • Billing challenges

Specialty Focus

Medical Specialties

Cardiology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Electrophysiology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Related ICD-10 Codes

Related CPT Codes

CPT Code

Clinical Scenario

Documentation Requirements

CPT Code

Clinical Scenario

Documentation Requirements

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

Pre-excitation syndromes can significantly impact patient quality of life due to recurrent arrhythmias and associated symptoms. Population health considerations include the potential for sudden cardiac events, which necessitate timely diagnosis and management. Quality measures focus on the effectiveness of treatment strategies, such as catheter ablation, in reducing arrhythmia recurrence. Understanding epidemiological patterns can aid in identifying at-risk populations and improving healthcare utilization through targeted interventions.

ICD-9 vs ICD-10

Pre-excitation syndromes can significantly impact patient quality of life due to recurrent arrhythmias and associated symptoms. Population health considerations include the potential for sudden cardiac events, which necessitate timely diagnosis and management. Quality measures focus on the effectiveness of treatment strategies, such as catheter ablation, in reducing arrhythmia recurrence. Understanding epidemiological patterns can aid in identifying at-risk populations and improving healthcare utilization through targeted interventions.

Reimbursement & Billing Impact

Reimbursement considerations include the complexity of the diagnostic workup and the interventions undertaken, such as catheter ablation. Common denials may arise from insufficient documentation or failure to demonstrate medical necessity for procedures. Best practices include ensuring that all relevant clinical information is included in the medical record and that coding accurately reflects the services provided.

Resources

Clinical References

  • •
    ICD-10 Official Guidelines for I00-I99
  • •
    Clinical Documentation Requirements

Coding & Billing References

  • •
    ICD-10 Official Guidelines for I00-I99
  • •
    Clinical Documentation Requirements

Frequently Asked Questions

What specific conditions are covered by I45.6?

I45.6 specifically covers pre-excitation syndromes, including Wolff-Parkinson-White syndrome and Lown-Ganong-Levine syndrome, which are characterized by abnormal conduction pathways leading to tachyarrhythmias.

When should I45.6 be used instead of related codes?

I45.6 should be used when a patient presents with symptoms and diagnostic findings indicative of pre-excitation syndromes, particularly when accessory pathways are confirmed through ECG or electrophysiological studies, differentiating it from other conduction disorders.

What documentation supports I45.6?

Documentation should include detailed clinical notes on patient symptoms, ECG findings, results from electrophysiological studies, and any previous treatment interventions. Clear evidence of the pre-excitation syndrome diagnosis is essential for proper coding.