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v1.0.0
ICD-10 Guide
ICD-10 CodesI51.81

I51.81

Billable

Takotsubo syndrome

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/06/2025

Code Description

ICD-10 I51.81 is a billable code used to indicate a diagnosis of takotsubo syndrome.

Key Diagnostic Point:

Takotsubo syndrome, also known as stress-induced cardiomyopathy, is a temporary heart condition often triggered by extreme emotional or physical stress. Symptoms mimic those of a heart attack, including chest pain and shortness of breath. Diagnosis is typically made through imaging studies and exclusion of other cardiac conditions. Treatment focuses on symptom management and may include medications to support heart function.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • severity of symptoms
  • patient's stress history

Audit Risk Factors

    Specialty Focus

    Related ICD-10 Codes

    Related CPT Codes

    93306CPT Code

    Clinical Scenario

    Documentation Requirements

    ICD-10 Impact

    Diagnostic & Documentation Impact

    Enhanced Specificity

    ICD-10 Improvements

    Generally has a good prognosis, but can lead to complications if not managed.

    ICD-9 vs ICD-10

    Generally has a good prognosis, but can lead to complications if not managed.

    Reimbursement & Billing Impact

    Generally has a good prognosis, but can lead to complications if not managed.

    Resources

    Clinical References

    • •
      Takotsubo Syndrome Foundation

    Coding & Billing References

    • •
      Takotsubo Syndrome Foundation

    Frequently Asked Questions

    What triggers Takotsubo syndrome?

    Common triggers include emotional stress, physical illness, or trauma.