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ICD-10 Guide
ICD-10 CodesI63.21

I63.21

Non-billable

Cerebral infarction due to unspecified occlusion or stenosis of vertebral arteries

BILLABLE STATUSNo
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/06/2025

Code Description

ICD-10 I63.21 is a used to indicate a diagnosis of cerebral infarction due to unspecified occlusion or stenosis of vertebral arteries.

Key Diagnostic Point:

Cerebral infarction due to unspecified occlusion or stenosis of the vertebral arteries occurs when blood flow to a part of the brain is obstructed due to narrowing or blockage of the vertebral arteries, which supply blood to the posterior circulation of the brain. Clinically, patients may present with sudden onset of neurological deficits, including weakness, sensory loss, dizziness, or visual disturbances, depending on the area of the brain affected. The vertebral arteries are critical for supplying blood to the brainstem and cerebellum, and occlusion can lead to significant morbidity. Disease progression can vary; some patients may experience transient ischemic attacks (TIAs) before a full-blown infarction occurs. Diagnostic considerations include imaging studies such as MRI or CT scans to visualize the infarct and angiography to assess the blood vessels. Risk factors include hypertension, hyperlipidemia, smoking, and diabetes, which contribute to vascular disease and increase the likelihood of occlusion or stenosis.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Diagnostic complexity: Requires imaging and clinical correlation to confirm diagnosis.
  • Treatment complexity: May involve anticoagulation, rehabilitation, and management of risk factors.
  • Documentation requirements: Detailed clinical notes and imaging reports are essential.
  • Coding specificity: Requires precise identification of the cause of the infarction.

Audit Risk Factors

  • Common coding errors: Misidentification of the type of stroke or occlusion.
  • Documentation gaps: Incomplete clinical notes or lack of imaging reports.
  • Billing challenges: Denials due to insufficient documentation or incorrect coding.

Specialty Focus

Medical Specialties

Neurology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Cardiology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Related ICD-10 Codes

Related CPT Codes

CPT Code

Clinical Scenario

Documentation Requirements

CPT Code

Clinical Scenario

Documentation Requirements

CPT Code

Clinical Scenario

Documentation Requirements

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

Cerebral infarction due to vertebral artery occlusion has significant clinical implications, affecting patient quality of life and increasing healthcare utilization. It is a major contributor to stroke-related morbidity and mortality. Understanding the epidemiology of this condition helps in developing targeted prevention strategies and improving population health outcomes.

ICD-9 vs ICD-10

Cerebral infarction due to vertebral artery occlusion has significant clinical implications, affecting patient quality of life and increasing healthcare utilization. It is a major contributor to stroke-related morbidity and mortality. Understanding the epidemiology of this condition helps in developing targeted prevention strategies and improving population health outcomes.

Reimbursement & Billing Impact

Reimbursement considerations include the severity of the condition and the necessity of interventions. Common denials may arise from insufficient documentation or failure to demonstrate medical necessity for imaging. Best practices include ensuring that all clinical notes are complete and that imaging results are clearly linked to the diagnosis.

Resources

Clinical References

  • •
    ICD-10 Official Guidelines for I00-I99
  • •
    Clinical Documentation Requirements

Coding & Billing References

  • •
    ICD-10 Official Guidelines for I00-I99
  • •
    Clinical Documentation Requirements

Frequently Asked Questions

What specific conditions are covered by I63.21?

I63.21 covers cerebral infarctions specifically due to occlusion or stenosis of the vertebral arteries. This includes cases where the exact cause of occlusion is not specified, but the infarction is confirmed through imaging.

When should I63.21 be used instead of related codes?

I63.21 should be used when there is a confirmed cerebral infarction attributed to unspecified occlusion or stenosis of the vertebral arteries, distinguishing it from codes related to other types of strokes or specific arterial occlusions.

What documentation supports I63.21?

Documentation should include clinical findings, imaging results confirming the infarction, and any relevant history of vascular disease or risk factors that may have contributed to the occlusion.