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ICD-10 Guide
ICD-10 CodesK75.4

K75.4

Billable

Autoimmune hepatitis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/06/2025

Code Description

ICD-10 K75.4 is a billable code used to indicate a diagnosis of autoimmune hepatitis.

Key Diagnostic Point:

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease characterized by the immune system attacking liver cells, leading to hepatocellular injury and inflammation. Clinically, patients may present with symptoms such as fatigue, jaundice, abdominal discomfort, and elevated liver enzymes. The disease primarily affects women and can occur at any age, although it is most commonly diagnosed in young adults. The liver anatomy involved includes hepatocytes, bile ducts, and portal tracts, which become infiltrated with lymphocytes and plasma cells in AIH. Disease progression can lead to fibrosis, cirrhosis, and ultimately liver failure if left untreated. Diagnostic considerations include serological markers such as antinuclear antibodies (ANA), smooth muscle antibodies (SMA), and liver biopsy findings that reveal interface hepatitis and plasma cell infiltration. Diagnosis often requires exclusion of other liver diseases, making a comprehensive clinical evaluation essential.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Diagnostic complexity: Requires serological testing and possibly liver biopsy for confirmation.
  • Treatment complexity: Management may involve immunosuppressive therapy, which requires careful monitoring.
  • Documentation requirements: Detailed clinical history and lab results must be documented to support diagnosis.
  • Coding specificity: Requires accurate coding to differentiate from other liver diseases.

Audit Risk Factors

  • Common coding errors: Misclassification with other types of hepatitis.
  • Documentation gaps: Incomplete lab results or lack of clinical correlation.
  • Billing challenges: Denials may arise from insufficient evidence of autoimmune etiology.

Specialty Focus

Medical Specialties

Hepatology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Gastroenterology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Related ICD-10 Codes

Related CPT Codes

CPT Code

Clinical Scenario

Documentation Requirements

CPT Code

Clinical Scenario

Documentation Requirements

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

Autoimmune hepatitis has significant clinical implications, as early diagnosis and treatment can prevent progression to cirrhosis and liver failure. The disease affects a small but notable population, with varying prevalence across demographics. Quality measures include monitoring liver function tests and patient adherence to treatment regimens. Understanding epidemiological patterns helps in resource allocation and healthcare planning, as well as in raising awareness about this condition among healthcare providers.

ICD-9 vs ICD-10

Autoimmune hepatitis has significant clinical implications, as early diagnosis and treatment can prevent progression to cirrhosis and liver failure. The disease affects a small but notable population, with varying prevalence across demographics. Quality measures include monitoring liver function tests and patient adherence to treatment regimens. Understanding epidemiological patterns helps in resource allocation and healthcare planning, as well as in raising awareness about this condition among healthcare providers.

Reimbursement & Billing Impact

Reimbursement considerations include the need for prior authorization for immunosuppressive therapies. Common denials may occur if documentation does not clearly establish the autoimmune nature of the hepatitis. Coders should ensure that all relevant lab results and clinical notes are included to support the diagnosis and treatment provided. Best practices include regular updates to the patient's medical record and clear communication with payers regarding the necessity of treatments.

Resources

Clinical References

  • •
    ICD-10 Official Guidelines for K00-K99
  • •
    Clinical Documentation Requirements

Coding & Billing References

  • •
    ICD-10 Official Guidelines for K00-K99
  • •
    Clinical Documentation Requirements

Frequently Asked Questions

What specific conditions are covered by K75.4?

K75.4 specifically covers autoimmune hepatitis, which may include variants such as type 1 and type 2 autoimmune hepatitis, characterized by different autoantibody profiles and clinical presentations.

When should K75.4 be used instead of related codes?

K75.4 should be used when there is clear evidence of autoimmune hepatitis, supported by serological markers and clinical findings, differentiating it from other liver conditions such as viral hepatitis or alcoholic liver disease.

What documentation supports K75.4?

Documentation should include a thorough clinical history, laboratory results indicating autoimmune markers, imaging studies if performed, and any liver biopsy results that confirm the diagnosis.