Stevens-Johnson syndrome-toxic epidermal necrolysis overlap syndrome
ICD-10 L51.3 is a billable code used to indicate a diagnosis of stevens-johnson syndrome-toxic epidermal necrolysis overlap syndrome.
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) overlap syndrome is a severe, life-threatening condition characterized by extensive skin detachment and mucosal involvement. Clinically, patients present with flu-like symptoms, followed by the rapid onset of painful erythematous macules that evolve into vesicles and bullae. The epidermis may slough off, leading to significant fluid loss and risk of secondary infections. The condition primarily affects the skin and mucous membranes, including the eyes, mouth, and genitalia. The pathophysiology involves a hypersensitivity reaction, often triggered by medications, infections, or other factors. Disease progression can lead to complications such as sepsis, organ failure, and long-term sequelae like scarring and vision loss. Diagnosis is based on clinical presentation, history of exposure to potential triggers, and sometimes skin biopsy. Early recognition and prompt treatment are crucial to improve outcomes and reduce morbidity and mortality associated with this syndrome.
Standard ICD-10-CM documentation requirements apply
Various clinical presentations within this specialty area
Follow specialty-specific billing guidelines
Standard ICD-10-CM documentation requirements apply
Various clinical presentations within this specialty area
Follow specialty-specific billing guidelines
L51.3 encompasses cases where patients exhibit features of both Stevens-Johnson syndrome and toxic epidermal necrolysis, typically characterized by significant skin and mucosal involvement, often triggered by medications or infections.
L51.3 should be used when a patient presents with overlapping symptoms of SJS and TEN, particularly when there is extensive skin detachment and mucosal involvement that does not fit neatly into either category alone.
Documentation should include a detailed clinical history, description of skin lesions, any associated symptoms, and a record of potential triggers. A thorough examination of mucosal involvement is also essential.
