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ICD-10 Guide
ICD-10 CodesN01.2

N01.2

Billable

Rapidly progressive nephritic syndrome with diffuse membranous glomerulonephritis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N01.2 is a billable code used to indicate a diagnosis of rapidly progressive nephritic syndrome with diffuse membranous glomerulonephritis.

Key Diagnostic Point:

Rapidly progressive nephritic syndrome (RPNS) is characterized by a swift decline in renal function, often leading to end-stage renal disease within weeks to months. This condition is associated with diffuse membranous glomerulonephritis, which is marked by the presence of subepithelial immune complex deposits along the glomerular capillary walls. Clinically, patients typically present with a triad of symptoms: hematuria, proteinuria, and renal insufficiency. Hematuria manifests as blood in the urine, while proteinuria can lead to nephrotic syndrome, characterized by significant protein loss in urine, edema, and hypoalbuminemia. Renal biopsy findings often reveal diffuse thickening of the glomerular capillary walls, with immunofluorescence microscopy showing granular deposits of IgG and complement components. Management of RPNS involves addressing the underlying cause, which may include immunosuppressive therapy, corticosteroids, and supportive care to manage complications such as hypertension and electrolyte imbalances.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Requires understanding of nephrology terminology and conditions
  • Differentiation from other types of glomerulonephritis
  • Need for accurate documentation of clinical findings
  • Potential for multiple underlying causes requiring specific coding

Audit Risk Factors

  • Inadequate documentation of renal biopsy results
  • Failure to document the clinical presentation accurately
  • Misclassification of the type of glomerulonephritis
  • Lack of evidence for the underlying cause of RPNS

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed clinical notes on symptoms, lab results, and biopsy findings.

Common Clinical Scenarios

Patients presenting with acute renal failure, hematuria, and proteinuria.

Billing Considerations

Ensure all laboratory results and imaging studies are documented to support the diagnosis.

Pathology

Documentation Requirements

Comprehensive reports on renal biopsy findings, including immunofluorescence and electron microscopy results.

Common Clinical Scenarios

Biopsy evaluations for patients with suspected glomerulonephritis.

Billing Considerations

Pathology reports must clearly indicate the type of glomerular disease to support nephrology coding.

Coding Guidelines

Inclusion Criteria

Use N01.2 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the diagnosis is supported by clinical documentation
  • Include details on the severity of the condition and any associated symptoms or complications

Exclusion Criteria

Do NOT use N01.2 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

88184CPT Code

Renal biopsy, percutaneous, needle

Clinical Scenario

Used when a renal biopsy is performed to confirm diagnosis.

Documentation Requirements

Biopsy report must be included in the patient's medical record.

Specialty Considerations

Nephrologists must document the indication for biopsy clearly.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of nephrology-related conditions, improving the accuracy of diagnoses and treatment tracking. N01.2 provides a clear distinction for rapidly progressive forms of nephritis, which is critical for appropriate management and reimbursement.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of nephrology-related conditions, improving the accuracy of diagnoses and treatment tracking. N01.2 provides a clear distinction for rapidly progressive forms of nephritis, which is critical for appropriate management and reimbursement.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    American Academy of Nephrology

Coding & Billing References

  • •
    American Academy of Nephrology

Frequently Asked Questions

What are the key symptoms of rapidly progressive nephritic syndrome?

Key symptoms include hematuria, significant proteinuria, edema, and a rapid decline in renal function.