Rapidly progressive nephritic syndrome with dense deposit disease
ICD-10 N01.6 is a billable code used to indicate a diagnosis of rapidly progressive nephritic syndrome with dense deposit disease.
Rapidly progressive nephritic syndrome (RPNS) with dense deposit disease is characterized by a rapid decline in renal function, often leading to end-stage renal disease within weeks to months. This condition is associated with the presence of dense deposits in the glomerular basement membrane, which is indicative of a specific type of glomerulonephritis. Clinically, patients may present with symptoms of nephritis, including hematuria, proteinuria, and hypertension. Laboratory findings typically reveal significant proteinuria and elevated serum creatinine levels. A renal biopsy is crucial for diagnosis, showing characteristic dense deposits on electron microscopy, along with mesangial proliferation and possible crescent formation. Management often involves immunosuppressive therapy, including corticosteroids and other agents, to mitigate the inflammatory process and preserve renal function. Early recognition and treatment are essential to improve outcomes in affected patients.
Detailed clinical notes including symptoms, lab results, and biopsy findings.
Patients presenting with acute renal failure and nephritic symptoms.
Ensure that all relevant laboratory and imaging studies are documented to support the diagnosis.
Comprehensive reports on renal biopsy findings, including histological and electron microscopy results.
Biopsy evaluations for patients suspected of having glomerulonephritis.
Pathology reports must clearly indicate the presence of dense deposits and any associated findings.
Used when a renal biopsy is performed to confirm the diagnosis of N01.6.
Document the indication for biopsy and findings.
Nephrologists must ensure that the biopsy results are clearly linked to the diagnosis.
Key symptoms include hematuria, proteinuria, hypertension, and rapid decline in renal function, often requiring immediate medical intervention.
