Nephrotic syndrome with dense deposit disease
ICD-10 N04.6 is a billable code used to indicate a diagnosis of nephrotic syndrome with dense deposit disease.
Nephrotic syndrome with dense deposit disease is a rare form of nephrotic syndrome characterized by the presence of dense deposits in the glomerular basement membrane. This condition is often associated with complement dysregulation, leading to glomerulonephritis and significant proteinuria. Patients typically present with symptoms such as edema, foamy urine due to proteinuria, and possible hematuria. Renal biopsy findings often reveal a characteristic pattern of dense deposits on electron microscopy, which distinguishes it from other forms of nephrotic syndrome. The pathophysiology involves the activation of the alternative complement pathway, resulting in inflammation and damage to the glomeruli. Management of nephrotic syndrome with dense deposit disease may include corticosteroids, immunosuppressive agents, and supportive care to control symptoms and prevent complications such as thromboembolism and infections. Regular monitoring of renal function and proteinuria is essential for assessing disease progression and treatment efficacy.
Detailed clinical notes on symptoms, lab results, and treatment plans.
Diagnosis and management of nephrotic syndrome, renal biopsies, and follow-up care.
Ensure clear documentation of proteinuria levels and renal function tests.
Comprehensive reports on renal biopsy findings, including histological and electron microscopy results.
Evaluation of renal biopsies for nephrotic syndrome and glomerulonephritis.
Accurate description of dense deposits and their implications for diagnosis.
Used when a renal biopsy is performed to confirm diagnosis.
Document indication for biopsy, findings, and any complications.
Nephrology specialists should ensure thorough documentation of the biopsy process.
Common symptoms include significant edema, foamy urine due to proteinuria, and possible hematuria. Patients may also experience fatigue and weight gain due to fluid retention.
