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ICD-10 Guide
ICD-10 CodesN05.6

N05.6

Billable

Unspecified nephritic syndrome with dense deposit disease

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N05.6 is a billable code used to indicate a diagnosis of unspecified nephritic syndrome with dense deposit disease.

Key Diagnostic Point:

Unspecified nephritic syndrome with dense deposit disease is a condition characterized by the presence of nephritis and nephrotic syndrome features, primarily due to dense deposit disease (DDD), a form of membranoproliferative glomerulonephritis. Patients typically present with symptoms such as proteinuria, hematuria, and edema. The pathophysiology involves the deposition of complement component C3 in the glomerular basement membrane, leading to inflammation and damage. Renal biopsy findings often reveal a characteristic pattern of glomerular changes, including mesangial proliferation and dense deposits in the glomerular capillary walls. Management by nephrology specialists may include corticosteroids, immunosuppressive agents, and supportive care to control symptoms and prevent progression to end-stage renal disease. Accurate coding is essential for appropriate treatment and reimbursement, as well as for tracking the epidemiology of this condition.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in clinical presentation and symptoms
  • Need for renal biopsy confirmation
  • Differentiation from other types of nephritic syndromes
  • Potential for overlapping diagnoses

Audit Risk Factors

  • Inadequate documentation of renal biopsy results
  • Failure to document the presence of proteinuria and hematuria
  • Misclassification of nephritic syndrome types
  • Lack of clarity in treatment plans

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed clinical notes including symptoms, lab results, and treatment plans.

Common Clinical Scenarios

Patients presenting with edema, hypertension, and abnormal urinalysis findings.

Billing Considerations

Ensure clear documentation of renal function tests and biopsy results to support the diagnosis.

Pathology

Documentation Requirements

Comprehensive reports on renal biopsy findings, including histological analysis.

Common Clinical Scenarios

Evaluation of renal biopsies for suspected glomerular diseases.

Billing Considerations

Pathology reports must clearly indicate the presence of dense deposits and any associated glomerular changes.

Coding Guidelines

Inclusion Criteria

Use N05.6 When
  • Follow official ICD
  • 10 coding guidelines, ensuring that the diagnosis is supported by clinical documentation and laboratory findings
  • Include specific details about the patient's condition and treatment plan

Exclusion Criteria

Do NOT use N05.6 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

88172CPT Code

Renal biopsy, percutaneous

Clinical Scenario

Used to confirm diagnosis of nephritic syndrome with dense deposit disease.

Documentation Requirements

Biopsy report must detail findings and correlate with clinical symptoms.

Specialty Considerations

Nephrologists must ensure that the biopsy is indicated based on clinical presentation.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of nephritic syndromes, improving the accuracy of diagnoses and treatment tracking. N05.6 provides a clear classification for dense deposit disease, which was less defined in ICD-9.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of nephritic syndromes, improving the accuracy of diagnoses and treatment tracking. N05.6 provides a clear classification for dense deposit disease, which was less defined in ICD-9.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    Kidney Disease: Improving Global Outcomes (KDIGO)

Coding & Billing References

  • •
    Kidney Disease: Improving Global Outcomes (KDIGO)

Frequently Asked Questions

What are the key symptoms of nephritic syndrome with dense deposit disease?

Key symptoms include hematuria, proteinuria, edema, and hypertension. Patients may also experience fatigue and decreased urine output.