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ICD-10 Guide
ICD-10 CodesChapter 14: Diseases of the genitourinary systemN06

N06

Billable

Isolated proteinuria with specified morphological lesion

Chapter 14:Diseases of the genitourinary system

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N06 is a billable code used to indicate a diagnosis of isolated proteinuria with specified morphological lesion.

Key Diagnostic Point:

Isolated proteinuria refers to the presence of excess protein in the urine without other significant urinary abnormalities. This condition can be indicative of underlying glomerular disorders, particularly when associated with specific morphological lesions observed in renal biopsies. These lesions may include minimal change disease, focal segmental glomerulosclerosis, or other glomerulonephritides. Isolated proteinuria can be hereditary, often linked to genetic mutations affecting kidney function. In cases where proteinuria is a symptom of a disease classified elsewhere, such as diabetes or hypertension, it is crucial to identify the primary condition to ensure accurate coding. Genetic testing may be warranted to identify hereditary nephropathies, especially in pediatric patients or those with a family history of kidney disease. The clinical evaluation of isolated proteinuria typically involves urinalysis, serum creatinine levels, and possibly renal imaging or biopsy to ascertain the underlying cause and guide treatment.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between primary and secondary causes of proteinuria
  • Identifying specific morphological lesions through renal biopsy
  • Understanding hereditary nephropathies and their genetic implications
  • Navigating coding guidelines for associated conditions

Audit Risk Factors

  • Inadequate documentation of renal biopsy findings
  • Failure to specify the type of proteinuria
  • Misclassification of hereditary nephropathies
  • Lack of correlation between clinical findings and coding

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed renal biopsy reports, urinalysis results, and clinical history of proteinuria.

Common Clinical Scenarios

Patients presenting with unexplained proteinuria, family history of kidney disease, or abnormal renal function tests.

Billing Considerations

Ensure that the specific morphological lesions are documented and correlate with the diagnosis.

Genetics

Documentation Requirements

Family history assessments, genetic testing results, and clinical evaluations of hereditary conditions.

Common Clinical Scenarios

Patients with a known family history of nephropathy or those presenting with early-onset kidney disease.

Billing Considerations

Document genetic testing results clearly to support coding for hereditary nephropathies.

Coding Guidelines

Inclusion Criteria

Use N06 When
  • According to ICD
  • 10 guidelines, N06 should be used when isolated proteinuria is documented with specific morphological lesions
  • It is essential to ensure that the documentation supports the diagnosis and that any associated conditions are coded appropriately

Exclusion Criteria

Do NOT use N06 When
  • Exclusion criteria include conditions where proteinuria is secondary to systemic diseases without specific morphological lesions

Related CPT Codes

88305CPT Code

Pathology examination of renal biopsy

Clinical Scenario

Used when a renal biopsy is performed to assess morphological lesions.

Documentation Requirements

Biopsy report detailing findings and correlation with clinical symptoms.

Specialty Considerations

Nephrologists must ensure that the biopsy findings are clearly linked to the diagnosis of isolated proteinuria.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like isolated proteinuria, enabling better tracking of glomerular disorders and hereditary nephropathies. This specificity aids in research and treatment planning.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like isolated proteinuria, enabling better tracking of glomerular disorders and hereditary nephropathies. This specificity aids in research and treatment planning.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of conditions like isolated proteinuria, enabling better tracking of glomerular disorders and hereditary nephropathies. This specificity aids in research and treatment planning.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the significance of specifying morphological lesions in coding N06?

Specifying morphological lesions is crucial as it directly impacts the accuracy of the diagnosis and treatment plan. It helps differentiate between various types of glomerular disorders and ensures appropriate management.