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ICD-10 Guide
ICD-10 CodesN06.6

N06.6

Billable

Isolated proteinuria with dense deposit disease

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N06.6 is a billable code used to indicate a diagnosis of isolated proteinuria with dense deposit disease.

Key Diagnostic Point:

Isolated proteinuria with dense deposit disease is a condition characterized by the presence of excess protein in the urine without significant renal impairment or other systemic symptoms. Dense deposit disease (DDD) is a rare form of glomerulonephritis associated with the deposition of complement component C3 in the glomerular basement membrane, leading to alterations in kidney function. Patients typically present with isolated proteinuria, which may be detected incidentally during routine urinalysis. The condition can be hereditary, often linked to mutations in genes associated with the complement system, and may manifest in childhood or adulthood. Diagnosis is confirmed through a combination of clinical evaluation, laboratory tests, and kidney biopsy, which reveals characteristic findings. Management focuses on monitoring protein levels and addressing any underlying causes, with treatment options varying based on the severity of proteinuria and associated symptoms. Regular follow-up is essential to assess kidney function and the potential progression of the disease.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Requires understanding of glomerular disorders and their classifications.
  • Differentiation from other types of proteinuria and nephropathy.
  • Need for precise documentation of clinical findings and laboratory results.
  • Potential for hereditary factors complicating the diagnosis.

Audit Risk Factors

  • Inadequate documentation of proteinuria severity.
  • Failure to document hereditary factors or family history.
  • Misclassification of proteinuria type.
  • Lack of follow-up documentation indicating ongoing management.

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed clinical notes on proteinuria assessment, laboratory results, and management plans.

Common Clinical Scenarios

Patients presenting with unexplained proteinuria during routine check-ups or those with a family history of kidney disease.

Billing Considerations

Ensure comprehensive documentation of renal function tests and any genetic testing performed.

Genetics

Documentation Requirements

Documentation of genetic testing results and family history of hereditary nephropathies.

Common Clinical Scenarios

Patients with a known family history of dense deposit disease or unexplained proteinuria.

Billing Considerations

Accurate coding of genetic tests and their implications for family members.

Coding Guidelines

Inclusion Criteria

Use N06.6 When
  • Follow official ICD
  • 10 coding guidelines, ensuring accurate documentation of the condition's specifics, including the presence of dense deposit disease and any associated symptoms

Exclusion Criteria

Do NOT use N06.6 When
  • Exclude conditions that do not meet the criteria for this diagnosis

Related ICD-10 Codes

Related CPT Codes

84156CPT Code

Urine protein, total

Clinical Scenario

Used to assess protein levels in patients with suspected proteinuria.

Documentation Requirements

Document the reason for testing and any relevant clinical findings.

Specialty Considerations

Nephrologists should ensure comprehensive documentation of the patient's renal status.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like isolated proteinuria with dense deposit disease, improving the accuracy of patient records and facilitating better management strategies.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like isolated proteinuria with dense deposit disease, improving the accuracy of patient records and facilitating better management strategies.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of conditions like isolated proteinuria with dense deposit disease, improving the accuracy of patient records and facilitating better management strategies.

Resources

Clinical References

  • •
    Dense Deposit Disease Overview

Coding & Billing References

  • •
    Dense Deposit Disease Overview

Frequently Asked Questions

What is the significance of isolated proteinuria?

Isolated proteinuria can be an early indicator of kidney disease, particularly glomerular disorders like dense deposit disease. It is crucial for early diagnosis and management.