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ICD-10 Guide
ICD-10 CodesN06.8

N06.8

Billable

Isolated proteinuria with other morphologic lesion

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N06.8 is a billable code used to indicate a diagnosis of isolated proteinuria with other morphologic lesion.

Key Diagnostic Point:

Isolated proteinuria refers to the presence of excess protein in the urine without accompanying signs of nephrotic syndrome or significant renal impairment. This condition can be indicative of underlying glomerular disorders, hereditary nephropathies, or other morphologic lesions that may not be classified under primary glomerular diseases. The presence of proteinuria can be transient or persistent and may arise from various etiologies, including diabetes, hypertension, or genetic predispositions. In cases where proteinuria is isolated, it is essential to conduct further investigations to determine the underlying cause, which may include genetic testing for hereditary nephropathies. The identification of morphologic lesions through renal biopsy can provide critical insights into the specific type of glomerular disorder present, guiding appropriate management and treatment strategies. Accurate coding of N06.8 is crucial for proper patient management and for understanding the epidemiology of renal diseases.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between isolated proteinuria and nephrotic syndrome.
  • Identifying the specific morphologic lesions associated with proteinuria.
  • Understanding the implications of hereditary nephropathies.
  • Navigating the coding for related glomerular disorders classified elsewhere.

Audit Risk Factors

  • Inadequate documentation of the underlying cause of proteinuria.
  • Failure to document the results of renal biopsies or imaging studies.
  • Misclassification of proteinuria as nephrotic syndrome.
  • Lack of genetic testing documentation when hereditary nephropathy is suspected.

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed clinical notes on proteinuria assessment, renal function tests, and biopsy results.

Common Clinical Scenarios

Patients presenting with isolated proteinuria during routine check-ups or those with a family history of kidney disease.

Billing Considerations

Ensure that all relevant laboratory results and imaging studies are documented to support the diagnosis.

Genetics

Documentation Requirements

Documentation of family history, genetic testing results, and clinical findings related to hereditary nephropathies.

Common Clinical Scenarios

Patients with a known family history of kidney disease undergoing genetic testing.

Billing Considerations

Accurate coding of genetic tests and their implications for patient management.

Coding Guidelines

Inclusion Criteria

Use N06.8 When
  • According to ICD
  • 10 guidelines, N06
  • 8 should be used when isolated proteinuria is documented alongside other morphologic lesions
  • Coders must ensure that the documentation supports the diagnosis and that other potential causes of proteinuria are ruled out

Exclusion Criteria

Do NOT use N06.8 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

84156CPT Code

Urine protein, total

Clinical Scenario

Used to assess protein levels in patients with suspected proteinuria.

Documentation Requirements

Document the reason for the test and any relevant clinical findings.

Specialty Considerations

Nephrologists should ensure comprehensive documentation of the patient's renal status.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like isolated proteinuria, improving the granularity of data for epidemiological studies and clinical management.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like isolated proteinuria, improving the granularity of data for epidemiological studies and clinical management.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of conditions like isolated proteinuria, improving the granularity of data for epidemiological studies and clinical management.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the significance of isolated proteinuria?

Isolated proteinuria can indicate underlying kidney issues, including glomerular disorders or hereditary nephropathies. It requires further evaluation to determine the cause and appropriate management.