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ICD-10 Guide
ICD-10 CodesN06.9

N06.9

Billable

Isolated proteinuria with unspecified morphologic lesion

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N06.9 is a billable code used to indicate a diagnosis of isolated proteinuria with unspecified morphologic lesion.

Key Diagnostic Point:

Isolated proteinuria refers to the presence of excess protein in the urine without accompanying signs of kidney dysfunction or systemic disease. This condition can be a marker for underlying glomerular disorders, hereditary nephropathies, or may occur as an isolated finding. The term 'unspecified morphologic lesion' indicates that while proteinuria is present, there is no specific identifiable lesion noted in the kidney tissue upon examination. Isolated proteinuria can be transient or persistent and may require further investigation to determine its etiology. Common causes include minimal change disease, focal segmental glomerulosclerosis, and diabetic nephropathy. Genetic factors may play a role, particularly in hereditary nephropathies, where mutations in genes responsible for kidney function can lead to proteinuria. Diagnosis typically involves urinalysis, urine protein-to-creatinine ratio, and possibly kidney biopsy if indicated. Understanding the underlying cause is crucial for management and treatment, as some conditions may progress to chronic kidney disease if left untreated.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between transient and persistent proteinuria
  • Identifying underlying causes, including hereditary factors
  • Need for additional diagnostic testing (e.g., genetic testing)
  • Variability in clinical presentation and associated symptoms

Audit Risk Factors

  • Inadequate documentation of the underlying cause of proteinuria
  • Failure to document the absence of systemic disease
  • Misclassification of proteinuria type (e.g., transient vs. persistent)
  • Lack of supporting lab results or imaging studies

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed history of renal function, urinalysis results, and any imaging or biopsy findings.

Common Clinical Scenarios

Patients presenting with proteinuria during routine check-ups or those with a family history of kidney disease.

Billing Considerations

Ensure that all relevant lab results are documented to support the diagnosis and any potential hereditary factors.

Genetics

Documentation Requirements

Family history of kidney disease, results of genetic testing, and any relevant clinical findings.

Common Clinical Scenarios

Patients with a known family history of hereditary nephropathy presenting with isolated proteinuria.

Billing Considerations

Documentation of genetic counseling and testing results is crucial for accurate coding.

Coding Guidelines

Inclusion Criteria

Use N06.9 When
  • According to ICD
  • 10 guidelines, N06
  • 9 should be used when proteinuria is isolated and no specific morphologic lesion is identified
  • It is important to document the absence of systemic disease and any relevant lab findings to support the diagnosis

Exclusion Criteria

Do NOT use N06.9 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

84156CPT Code

Urine protein, total

Clinical Scenario

Used to quantify proteinuria in patients suspected of having renal disease.

Documentation Requirements

Document the reason for the test and any relevant clinical findings.

Specialty Considerations

Nephrologists should ensure that the test results correlate with the clinical diagnosis.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of isolated proteinuria, improving the ability to track and manage renal conditions effectively.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of isolated proteinuria, improving the ability to track and manage renal conditions effectively.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of isolated proteinuria, improving the ability to track and manage renal conditions effectively.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the significance of isolated proteinuria?

Isolated proteinuria can indicate underlying kidney disease or glomerular disorders. It is essential to evaluate the cause to prevent potential progression to chronic kidney disease.