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v1.0.0
ICD-10 Guide
ICD-10 CodesN14.0

N14.0

Billable

Analgesic nephropathy

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N14.0 is a billable code used to indicate a diagnosis of analgesic nephropathy.

Key Diagnostic Point:

Analgesic nephropathy is a form of kidney damage that occurs due to the chronic use of analgesic medications, particularly nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen. This condition is characterized by interstitial nephritis, which is inflammation of the kidney's interstitial tissue, and can lead to renal impairment. Patients may present with symptoms such as flank pain, hematuria, and signs of urinary tract infections (UTIs). The condition can also be associated with pyelonephritis, which is an infection of the kidney, and hydronephrosis, a swelling of the kidney due to urine buildup. The pathophysiology involves direct nephrotoxic effects of analgesics, leading to tubular damage and interstitial fibrosis. Diagnosis typically involves a combination of clinical history, laboratory tests, and imaging studies. Management may include discontinuation of the offending analgesics, treatment of any underlying infections, and supportive care for renal function. In severe cases, patients may require dialysis or other interventions to manage renal failure.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between analgesic nephropathy and other forms of nephropathy.
  • Need for comprehensive documentation of medication history.
  • Potential overlap with other renal conditions such as pyelonephritis and interstitial nephritis.
  • Variability in clinical presentation and laboratory findings.

Audit Risk Factors

  • Inadequate documentation of analgesic use.
  • Failure to document the duration of analgesic therapy.
  • Misclassification of nephropathy type.
  • Lack of supporting laboratory results.

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed history of analgesic use, renal function tests, and imaging studies.

Common Clinical Scenarios

Patients presenting with renal impairment and a history of chronic analgesic use.

Billing Considerations

Ensure clear documentation of the relationship between analgesic use and renal symptoms.

Primary Care

Documentation Requirements

Comprehensive medication history and assessment of renal function.

Common Clinical Scenarios

Patients with chronic pain management on analgesics presenting with renal symptoms.

Billing Considerations

Document any referrals to nephrology for further evaluation.

Coding Guidelines

Inclusion Criteria

Use N14.0 When
  • According to ICD
  • 10 coding guidelines, N14
  • 0 should be used when there is clear evidence of renal impairment linked to analgesic use
  • Documentation must support the diagnosis, including medication history and clinical findings

Exclusion Criteria

Do NOT use N14.0 When
  • Exclusion criteria include other identifiable causes of nephropathy

Related ICD-10 Codes

Related CPT Codes

80048CPT Code

Basic metabolic panel

Clinical Scenario

Used to assess renal function in patients suspected of analgesic nephropathy.

Documentation Requirements

Document the reason for testing and any relevant clinical findings.

Specialty Considerations

Nephrology may require additional tests based on initial findings.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of analgesic nephropathy, improving the ability to track and manage this condition. It emphasizes the importance of detailed documentation regarding medication use and renal function.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of analgesic nephropathy, improving the ability to track and manage this condition. It emphasizes the importance of detailed documentation regarding medication use and renal function.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of analgesic nephropathy, improving the ability to track and manage this condition. It emphasizes the importance of detailed documentation regarding medication use and renal function.

Resources

Clinical References

  • •
    Kidney Disease: Improving Global Outcomes (KDIGO)

Coding & Billing References

  • •
    Kidney Disease: Improving Global Outcomes (KDIGO)

Frequently Asked Questions

What is the primary cause of analgesic nephropathy?

The primary cause of analgesic nephropathy is the chronic use of analgesic medications, particularly NSAIDs and acetaminophen, which can lead to kidney damage over time.