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ICD-10 Guide
ICD-10 CodesN14.19

N14.19

Billable

Nephropathy induced by other drugs, medicaments and biological substances

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N14.19 is a billable code used to indicate a diagnosis of nephropathy induced by other drugs, medicaments and biological substances.

Key Diagnostic Point:

Nephropathy induced by other drugs, medicaments, and biological substances refers to kidney damage resulting from exposure to various pharmacological agents. This condition can manifest as acute interstitial nephritis, pyelonephritis, or chronic kidney disease, depending on the duration and type of drug exposure. Common culprits include non-steroidal anti-inflammatory drugs (NSAIDs), certain antibiotics, and chemotherapeutic agents. Symptoms may include flank pain, hematuria, and changes in urinary output. Diagnosis typically involves a combination of clinical evaluation, laboratory tests, and imaging studies to assess kidney function and structure. Management often requires discontinuation of the offending agent, supportive care, and in some cases, the use of corticosteroids to reduce inflammation. Close monitoring of renal function is essential to prevent progression to more severe renal impairment.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of drugs that can induce nephropathy
  • Overlap with other renal conditions
  • Need for detailed patient history
  • Potential for multiple diagnoses

Audit Risk Factors

  • Inadequate documentation of drug history
  • Failure to specify the type of nephropathy
  • Misclassification of acute vs. chronic conditions
  • Lack of supporting lab results

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed history of drug exposure, lab results, and imaging studies.

Common Clinical Scenarios

Patients presenting with acute kidney injury after starting new medications.

Billing Considerations

Ensure clear documentation of the timeline of drug exposure and renal function tests.

Internal Medicine

Documentation Requirements

Comprehensive medication lists and assessment of renal function.

Common Clinical Scenarios

Patients with chronic conditions requiring multiple medications presenting with renal impairment.

Billing Considerations

Documenting the rationale for medication changes and monitoring renal function closely.

Coding Guidelines

Inclusion Criteria

Use N14.19 When
  • Follow official ICD
  • CM coding guidelines, ensuring accurate documentation of the cause of nephropathy and any related conditions
  • Include relevant lab results and patient history to support the diagnosis

Exclusion Criteria

Do NOT use N14.19 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

80048CPT Code

Comprehensive metabolic panel

Clinical Scenario

Used to assess renal function in patients suspected of drug-induced nephropathy.

Documentation Requirements

Document the reason for the metabolic panel and any abnormal findings.

Specialty Considerations

Nephrologists may require additional renal function tests.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 allows for more specific coding of drug-induced nephropathy, improving the accuracy of data collection and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 allows for more specific coding of drug-induced nephropathy, improving the accuracy of data collection and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What types of drugs can cause nephropathy?

Various drugs, including NSAIDs, certain antibiotics, and chemotherapeutic agents, can lead to nephropathy. It is essential to review the patient's medication history for potential culprits.