Prostatic intraepithelial neoplasia
ICD-10 N42.31 is a billable code used to indicate a diagnosis of prostatic intraepithelial neoplasia.
Prostatic intraepithelial neoplasia (PIN) is a histological diagnosis characterized by abnormal proliferation of epithelial cells within the prostate gland. It is considered a precursor lesion to prostate cancer and is classified into low-grade and high-grade categories. Low-grade PIN is often found incidentally during prostate biopsies and is not associated with an increased risk of prostate cancer, while high-grade PIN is associated with a higher risk of developing prostate cancer. Clinically, patients may present with symptoms related to benign prostatic hyperplasia (BPH), such as urinary frequency, urgency, and nocturia. The diagnosis of PIN is typically made through histopathological examination of prostate tissue obtained via biopsy. Elevated prostate-specific antigen (PSA) levels may prompt further investigation, including biopsy, to rule out malignancy. Management of patients with PIN focuses on monitoring PSA levels and symptoms, as well as educating patients about the potential risks of prostate cancer. Regular follow-up is essential to detect any progression to prostate cancer early.
Detailed pathology reports, PSA levels, clinical symptoms, and follow-up plans.
Patients presenting with elevated PSA levels, abnormal digital rectal exams, or urinary symptoms.
Urologists must ensure accurate grading of PIN and document any changes in patient management based on biopsy results.
Comprehensive histopathological reports detailing the presence and grade of PIN.
Pathologists evaluating prostate biopsy specimens for cancer and PIN.
Pathologists should clearly differentiate between low-grade and high-grade PIN in their reports to guide clinical management.
Used when a biopsy is performed to diagnose PIN.
Pathology report confirming the diagnosis of PIN.
Urologists must ensure accurate coding based on biopsy findings.
High-grade prostatic intraepithelial neoplasia is considered a precursor to prostate cancer, indicating a higher risk for developing malignancy. Patients diagnosed with high-grade PIN require closer monitoring and follow-up.
