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ICD-10 Guide
ICD-10 CodesN46.022

N46.022

Billable

Azoospermia due to infection

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N46.022 is a billable code used to indicate a diagnosis of azoospermia due to infection.

Key Diagnostic Point:

Azoospermia due to infection is a condition characterized by the absence of sperm in the ejaculate, specifically attributed to an infectious process affecting the male reproductive system. This condition can arise from various infections, including sexually transmitted infections (STIs) such as gonorrhea and chlamydia, as well as other bacterial or viral infections that may lead to inflammation and obstruction of the reproductive tract. Infections can cause orchitis, epididymitis, or prostatitis, which may disrupt normal spermatogenesis and sperm transport. The diagnosis of azoospermia due to infection typically involves a thorough medical history, physical examination, and semen analysis, alongside laboratory tests to identify the causative pathogens. Management may include antibiotic therapy to treat the underlying infection, and in some cases, assisted reproductive technologies may be necessary if natural conception is not possible. Understanding the interplay between infections and male infertility is crucial for effective treatment and counseling.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between types of infections causing azoospermia.
  • Understanding the relationship between infections and other male reproductive disorders.
  • Need for comprehensive documentation of clinical findings and laboratory results.
  • Potential for co-existing conditions that may complicate coding.

Audit Risk Factors

  • Inadequate documentation of the infectious etiology.
  • Failure to document the relationship between infection and azoospermia.
  • Lack of clarity in treatment plans and follow-up care.
  • Misclassification of the type of azoospermia.

Specialty Focus

Medical Specialties

Urology

Documentation Requirements

Detailed patient history, physical examination findings, semen analysis results, and laboratory tests for infections.

Common Clinical Scenarios

Evaluation of male infertility, management of testicular pain, and treatment of sexually transmitted infections.

Billing Considerations

Urologists must ensure comprehensive documentation of all findings related to the reproductive system and any infectious processes.

Andrology

Documentation Requirements

Assessment of hormonal levels, semen analysis, and detailed history of sexual health and infections.

Common Clinical Scenarios

Management of male infertility, evaluation of hormonal imbalances, and treatment of penile disorders.

Billing Considerations

Andrologists should focus on the interplay between hormonal factors and infections affecting fertility.

Coding Guidelines

Inclusion Criteria

Use N46.022 When
  • According to ICD
  • 10 guidelines, N46
  • 022 should be used when azoospermia is specifically due to an infectious process
  • Coders must ensure that the documentation clearly supports the diagnosis and that all relevant laboratory findings are included
  • infectious causes

Exclusion Criteria

Do NOT use N46.022 When
  • Exclusion criteria include azoospermia due to non

Related ICD-10 Codes

Related CPT Codes

89320CPT Code

Semen analysis, including sperm count

Clinical Scenario

Used when evaluating male infertility and azoospermia.

Documentation Requirements

Document the reason for the semen analysis and any relevant patient history.

Specialty Considerations

Urologists and andrologists should ensure that the analysis is linked to the diagnosis of azoospermia.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like azoospermia due to infection, improving the accuracy of data collection and reimbursement processes. This specificity aids in better understanding the epidemiology of male infertility related to infections.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like azoospermia due to infection, improving the accuracy of data collection and reimbursement processes. This specificity aids in better understanding the epidemiology of male infertility related to infections.

Reimbursement & Billing Impact

reimbursement processes. This specificity aids in better understanding the epidemiology of male infertility related to infections.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the primary cause of azoospermia due to infection?

The primary cause is typically an infectious process affecting the male reproductive system, such as sexually transmitted infections or other bacterial infections that lead to inflammation and obstruction.