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ICD-10 Guide
ICD-10 CodesO26.641

O26.641

Billable

Intrahepatic cholestasis of pregnancy, first trimester

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/08/2025

Code Description

ICD-10 O26.641 is a billable code used to indicate a diagnosis of intrahepatic cholestasis of pregnancy, first trimester.

Key Diagnostic Point:

Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder that occurs during pregnancy, characterized by intense itching and elevated bile acids in the bloodstream. It typically manifests in the second or third trimester but can occur as early as the first trimester. The condition is thought to be related to hormonal changes and genetic predisposition, leading to impaired bile flow. Symptoms include pruritus, particularly on the palms and soles, and may be accompanied by jaundice in more severe cases. ICP poses risks to both the mother and fetus, including preterm birth and fetal distress due to bile acid toxicity. Management often involves monitoring liver function tests, bile acid levels, and fetal well-being, with treatment options including ursodeoxycholic acid to alleviate symptoms and reduce bile acid levels. Close collaboration among obstetricians, maternal-fetal medicine specialists, and hepatologists is essential for optimal maternal and fetal outcomes.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating ICP from other pruritic conditions in pregnancy.
  • Understanding the implications of elevated bile acids on fetal health.
  • Navigating treatment options and their documentation.
  • Monitoring and coding for associated complications.

Audit Risk Factors

  • Inadequate documentation of symptoms and laboratory results.
  • Failure to document interdisciplinary consultations.
  • Misclassification of the condition as a non-obstetric issue.
  • Omission of associated complications in coding.

Specialty Focus

Medical Specialties

Obstetrics and Gynecology

Documentation Requirements

Detailed documentation of symptoms, lab results, and treatment plans is essential. Include any consultations with specialists.

Common Clinical Scenarios

A pregnant patient presents with severe itching and elevated liver enzymes; management and monitoring protocols are initiated.

Billing Considerations

Ensure that all symptoms are documented clearly, and any changes in treatment are noted to support coding.

Maternal-Fetal Medicine

Documentation Requirements

High-risk pregnancy documentation must include comprehensive assessments of both maternal and fetal health, including ultrasound findings and fetal monitoring.

Common Clinical Scenarios

A patient with ICP is monitored for fetal distress due to elevated bile acids; interventions are documented.

Billing Considerations

Focus on the potential impact of ICP on fetal outcomes and ensure that all relevant data is captured.

Coding Guidelines

Inclusion Criteria

Use O26.641 When
  • Follow the official ICD
  • CM guidelines for coding obstetric conditions, ensuring that the trimester is accurately documented
  • Include any relevant complications and associated conditions

Exclusion Criteria

Do NOT use O26.641 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

99213CPT Code

Established patient office visit, Level 3

Clinical Scenario

Used for follow-up visits in patients diagnosed with ICP.

Documentation Requirements

Document the patient's symptoms, lab results, and treatment plan.

Specialty Considerations

Ensure that the visit is clearly linked to the management of ICP.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like ICP, improving the accuracy of data collection and reimbursement processes. It emphasizes the importance of documenting the trimester and associated complications.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like ICP, improving the accuracy of data collection and reimbursement processes. It emphasizes the importance of documenting the trimester and associated complications.

Reimbursement & Billing Impact

reimbursement processes. It emphasizes the importance of documenting the trimester and associated complications.

Resources

Clinical References

  • •
    American College of Obstetricians and Gynecologists (ACOG)

Coding & Billing References

  • •
    American College of Obstetricians and Gynecologists (ACOG)

Frequently Asked Questions

What are the common symptoms of intrahepatic cholestasis of pregnancy?

Common symptoms include intense itching, particularly on the palms and soles, and in some cases, jaundice. These symptoms can significantly impact the quality of life during pregnancy.