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ICD-10 Guide
ICD-10 CodesP04.15

P04.15

Billable

Newborn affected by maternal use of antidepressants

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 P04.15 is a billable code used to indicate a diagnosis of newborn affected by maternal use of antidepressants.

Key Diagnostic Point:

Newborns affected by maternal use of antidepressants may present with a range of symptoms due to in utero exposure to these medications. Antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs), can cross the placenta and affect fetal development. Common manifestations in affected newborns include respiratory distress, feeding difficulties, irritability, and potential withdrawal symptoms. These infants may also exhibit signs of neonatal abstinence syndrome (NAS), which can complicate their clinical management. The timing of maternal medication use during pregnancy, dosage, and the specific type of antidepressant can influence the severity of symptoms. Clinicians must monitor these newborns closely for any complications and provide appropriate interventions, including supportive care and, if necessary, pharmacological treatment to manage withdrawal symptoms. Documentation should include maternal medication history, timing of exposure, and any observed symptoms in the newborn to ensure accurate coding and care planning.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in maternal medication types and dosages.
  • Potential overlap with other substance exposure codes.
  • Need for detailed maternal history and newborn assessment.
  • Differentiation between withdrawal symptoms and other neonatal conditions.

Audit Risk Factors

  • Inadequate documentation of maternal medication history.
  • Failure to differentiate between withdrawal and other conditions.
  • Misclassification of symptoms leading to incorrect coding.
  • Lack of follow-up documentation on newborn outcomes.

Specialty Focus

Medical Specialties

Neonatology

Documentation Requirements

Detailed records of maternal medication use, timing, and newborn symptoms.

Common Clinical Scenarios

Newborns presenting with irritability, feeding difficulties, or respiratory distress in the NICU.

Billing Considerations

Consideration of potential co-occurring conditions and the need for multidisciplinary care.

Pediatrics

Documentation Requirements

Comprehensive assessment of developmental milestones and ongoing monitoring of behavioral health.

Common Clinical Scenarios

Pediatric follow-up visits for newborns with a history of maternal antidepressant use.

Billing Considerations

Awareness of long-term developmental impacts and the need for early intervention services.

Coding Guidelines

Inclusion Criteria

Use P04.15 When
  • According to ICD
  • 10 coding guidelines, accurate documentation of maternal medication use, timing of exposure, and clinical symptoms in the newborn is essential for proper coding
  • Coders should ensure that all relevant information is captured in the medical record to support the use of P04

Exclusion Criteria

Do NOT use P04.15 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

99460CPT Code

Initial hospital care, newborn

Clinical Scenario

Used for newborns requiring assessment and management of symptoms related to maternal antidepressant use.

Documentation Requirements

Complete documentation of maternal history and newborn assessment findings.

Specialty Considerations

Neonatologists should ensure thorough evaluations to support coding.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of perinatal conditions, including those related to maternal substance use. P04.15 provides a clear framework for documenting the impact of antidepressants on newborns, improving data accuracy and care planning.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of perinatal conditions, including those related to maternal substance use. P04.15 provides a clear framework for documenting the impact of antidepressants on newborns, improving data accuracy and care planning.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of perinatal conditions, including those related to maternal substance use. P04.15 provides a clear framework for documenting the impact of antidepressants on newborns, improving data accuracy and care planning.

Resources

Clinical References

  • •
    American Academy of Pediatrics - Guidelines for Perinatal Care

Coding & Billing References

  • •
    American Academy of Pediatrics - Guidelines for Perinatal Care

Frequently Asked Questions

What are the common symptoms in newborns affected by maternal antidepressant use?

Common symptoms include irritability, feeding difficulties, respiratory distress, and signs of withdrawal. Close monitoring is essential to manage these symptoms effectively.