ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesChapter 16: Certain conditions originating in the perinatal periodP25

P25

Billable

Interstitial emphysema and related conditions originating in the perinatal period

Chapter 16:Certain conditions originating in the perinatal period

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 P25 is a billable code used to indicate a diagnosis of interstitial emphysema and related conditions originating in the perinatal period.

Key Diagnostic Point:

Interstitial emphysema is a condition characterized by the presence of air in the interstitial spaces of the lungs, which can occur in newborns, particularly those who are premature or have experienced mechanical ventilation. This condition can arise due to barotrauma from positive pressure ventilation, leading to alveolar rupture and subsequent air leakage into the surrounding lung tissue. Clinically, interstitial emphysema may present with respiratory distress, decreased oxygen saturation, and abnormal lung sounds upon auscultation. It is crucial to monitor affected infants closely, as the condition can progress to more severe respiratory complications, including pneumothorax. Management typically involves supportive care, including oxygen therapy and, in some cases, mechanical ventilation adjustments. Early recognition and intervention are vital to prevent further respiratory compromise and ensure optimal outcomes for these vulnerable patients.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in clinical presentation among neonates
  • Need for precise documentation of respiratory support methods
  • Differentiation from other respiratory conditions
  • Potential for rapid clinical changes requiring ongoing assessment

Audit Risk Factors

  • Inadequate documentation of respiratory interventions
  • Failure to specify the severity of the condition
  • Misclassification of interstitial emphysema as pneumothorax
  • Lack of follow-up documentation on patient progress

Specialty Focus

Medical Specialties

Neonatology

Documentation Requirements

Detailed records of respiratory support, clinical assessments, and interventions are essential for accurate coding.

Common Clinical Scenarios

Infants requiring mechanical ventilation due to respiratory distress syndrome or meconium aspiration syndrome.

Billing Considerations

Coders must be aware of the nuances in documentation related to the timing and type of respiratory support provided.

Pediatrics

Documentation Requirements

Documentation should include a comprehensive history of respiratory issues and any interventions performed.

Common Clinical Scenarios

Pediatric follow-up visits for infants previously diagnosed with interstitial emphysema.

Billing Considerations

Consideration of the long-term respiratory outcomes and any ongoing treatments is important for accurate coding.

Coding Guidelines

Inclusion Criteria

Use P25 When
  • Coders should adhere to the official ICD
  • CM guidelines for perinatal coding, ensuring that all relevant clinical details are captured
  • Accurate coding requires a thorough understanding of the infant's clinical history, treatment interventions, and any complications that arise

Exclusion Criteria

Do NOT use P25 When
No specific exclusions found.

Related CPT Codes

94660CPT Code

Continuous positive airway pressure (CPAP) ventilation

Clinical Scenario

Used in the management of infants with interstitial emphysema to support breathing.

Documentation Requirements

Document the initiation and adjustments of CPAP settings and the infant's response.

Specialty Considerations

Neonatologists should ensure that all respiratory interventions are clearly documented to support coding.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of neonatal conditions, including interstitial emphysema. This specificity aids in better tracking of outcomes and resource utilization in neonatal care.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of neonatal conditions, including interstitial emphysema. This specificity aids in better tracking of outcomes and resource utilization in neonatal care.

Reimbursement & Billing Impact

reimbursement and quality reporting.

Resources

Clinical References

  • •
    American Academy of Pediatrics - Neonatal Coding Guidelines

Coding & Billing References

  • •
    American Academy of Pediatrics - Neonatal Coding Guidelines

Frequently Asked Questions

What are the common causes of interstitial emphysema in neonates?

Common causes include mechanical ventilation, particularly in premature infants, and conditions that lead to barotrauma, such as respiratory distress syndrome and meconium aspiration syndrome.