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ICD-10 Guide
ICD-10 CodesP52.21

P52.21

Billable

Intraventricular (nontraumatic) hemorrhage, grade 3, of newborn

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 P52.21 is a billable code used to indicate a diagnosis of intraventricular (nontraumatic) hemorrhage, grade 3, of newborn.

Key Diagnostic Point:

Intraventricular hemorrhage (IVH) is a common condition in premature infants, particularly those born before 32 weeks of gestation. Grade 3 IVH is characterized by the presence of blood in the ventricles of the brain, which can lead to significant complications, including hydrocephalus and long-term neurological deficits. This condition arises from the fragility of the germinal matrix, a highly vascular area in the brain that is particularly susceptible to injury. Factors contributing to IVH include low birth weight, rapid fluctuations in blood pressure, and hypoxia. Clinically, infants may present with signs such as lethargy, hypotonia, seizures, or bulging fontanelles. Diagnosis is typically confirmed through cranial ultrasound, which can visualize the extent of hemorrhage. Management may involve supportive care, monitoring for complications, and in some cases, surgical intervention to manage hydrocephalus. Early detection and intervention are critical to improving outcomes for affected infants.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Differentiating between grades of IVH requires detailed clinical documentation.
  • The need for accurate gestational age assessment to determine risk factors.
  • Potential for co-morbid conditions that may complicate coding.
  • Variability in clinical presentation and management strategies.

Audit Risk Factors

  • Inadequate documentation of clinical findings related to IVH.
  • Failure to capture the severity of the hemorrhage.
  • Misclassification of the grade of IVH.
  • Omission of associated conditions or complications.

Specialty Focus

Medical Specialties

Neonatology

Documentation Requirements

Detailed notes on gestational age, birth weight, and clinical signs of IVH.

Common Clinical Scenarios

Infants born at less than 32 weeks gestation presenting with neurological symptoms.

Billing Considerations

Ensure that cranial imaging results are included in the medical record.

Pediatrics

Documentation Requirements

Comprehensive history and physical examination findings related to neurological development.

Common Clinical Scenarios

Follow-up visits for infants with a history of IVH to monitor developmental milestones.

Billing Considerations

Consider long-term follow-up for potential developmental delays.

Coding Guidelines

Inclusion Criteria

Use P52.21 When
  • Follow the official ICD
  • CM guidelines for coding perinatal conditions, ensuring that documentation supports the diagnosis and reflects the severity of the condition

Exclusion Criteria

Do NOT use P52.21 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

76506CPT Code

Ultrasound, cranial, infant

Clinical Scenario

Used to assess for IVH in premature infants.

Documentation Requirements

Document indications for ultrasound and findings.

Specialty Considerations

Neonatologists should ensure imaging results are included in the medical record.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of IVH, enabling better tracking of outcomes and complications associated with this condition.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of IVH, enabling better tracking of outcomes and complications associated with this condition.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of IVH, enabling better tracking of outcomes and complications associated with this condition.

Resources

Clinical References

  • •
    American Academy of Pediatrics - Neonatal Care

Coding & Billing References

  • •
    American Academy of Pediatrics - Neonatal Care

Frequently Asked Questions

What are the long-term implications of grade 3 IVH in newborns?

Grade 3 IVH can lead to significant long-term neurological issues, including cerebral palsy, developmental delays, and cognitive impairments. Early intervention and monitoring are crucial for optimizing outcomes.