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v1.0.0
ICD-10 Guide
ICD-10 CodesR45.1

R45.1

Restlessness and agitation

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 R45.1 is a billable code used to indicate a diagnosis of restlessness and agitation.

Key Diagnostic Point:

Restlessness and agitation are symptoms characterized by an inability to remain still, often accompanied by feelings of anxiety or unease. Patients may exhibit physical signs such as fidgeting, pacing, or an inability to focus. These symptoms can arise from various underlying conditions, including psychiatric disorders (e.g., anxiety disorders, schizophrenia), neurological conditions (e.g., Parkinson's disease, dementia), or as a side effect of medications. Clinical assessment typically involves a thorough history and physical examination, focusing on the onset, duration, and context of the symptoms. Laboratory tests may be warranted to rule out metabolic or infectious causes. Understanding the patient's overall clinical picture is crucial for appropriate management and treatment planning.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying causes that can lead to restlessness and agitation.
  • Potential overlap with other psychiatric and neurological conditions.
  • Need for comprehensive documentation to support the diagnosis.
  • Variability in presentation among different patient populations.

Audit Risk Factors

  • Inadequate documentation of the underlying cause.
  • Failure to specify the context of restlessness and agitation.
  • Misuse of the code when symptoms are part of a broader psychiatric diagnosis.
  • Lack of supporting clinical evidence in the medical record.

Specialty Focus

Medical Specialties

Internal Medicine

Documentation Requirements

Detailed patient history, including medication review and psychosocial factors.

Common Clinical Scenarios

Patients presenting with anxiety, insomnia, or side effects from medications.

Billing Considerations

Consideration of comorbid conditions such as depression or chronic illness.

Emergency Medicine

Documentation Requirements

Acute assessment notes, including vital signs and immediate interventions.

Common Clinical Scenarios

Patients presenting with acute agitation due to substance use or withdrawal.

Billing Considerations

Rapid assessment and intervention are critical; documentation must reflect urgency.

Coding Guidelines

Inclusion Criteria

Use R45.1 When
  • Follow official ICD
  • CM guidelines for coding symptoms and signs
  • Ensure that the code is used when no specific diagnosis is available, and document the clinical rationale for its use

Exclusion Criteria

Do NOT use R45.1 When
No specific exclusions found.

Related CPT Codes

99213CPT Code

Established patient office visit, Level 3

Clinical Scenario

Used when evaluating a patient with restlessness and agitation in an outpatient setting.

Documentation Requirements

Document history, examination findings, and treatment plan.

Specialty Considerations

Internal medicine may focus on underlying medical causes, while psychiatry may focus on mental health aspects.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of symptoms like restlessness and agitation, improving the ability to capture the complexity of patient presentations.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of symptoms like restlessness and agitation, improving the ability to capture the complexity of patient presentations.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of symptoms like restlessness and agitation, improving the ability to capture the complexity of patient presentations.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

When should R45.1 be used?

R45.1 should be used when a patient presents with restlessness and agitation without a specific underlying diagnosis. It is important to document the context and any contributing factors.