Febrile nonhemolytic transfusion reaction
ICD-10 R50.84 is a billable code used to indicate a diagnosis of febrile nonhemolytic transfusion reaction.
Febrile nonhemolytic transfusion reaction (FNHTR) is a common complication of blood transfusions characterized by the onset of fever, chills, and malaise typically occurring within a few hours after the transfusion begins. This reaction is primarily due to the recipient's immune response to donor white blood cells, cytokines, or other components in the transfused blood product. Symptoms may include a rise in temperature of 1°C or more, rigors, and sometimes headache or myalgia. Laboratory findings may show no significant abnormalities, although leukocyte antibodies may be detected. FNHTR is generally self-limiting and resolves with supportive care, including antipyretics. It is essential to differentiate FNHTR from hemolytic transfusion reactions, which are more severe and can lead to serious complications. Proper identification and documentation of FNHTR are crucial for patient safety and quality of care.
Detailed documentation of patient symptoms, vital signs, and any interventions taken post-transfusion.
Patients receiving multiple transfusions for chronic anemia or during surgical procedures.
Consideration of underlying conditions that may predispose patients to febrile reactions.
Acute care documentation must include time of transfusion, onset of symptoms, and immediate interventions.
Patients presenting with fever shortly after blood transfusion in the emergency department.
Rapid assessment and documentation are critical to differentiate from other acute febrile illnesses.
Used when documenting the transfusion procedure that may lead to FNHTR.
Document the type of blood product, volume, and patient response.
Ensure that the transfusion is documented in the context of the patient's overall treatment plan.
Common symptoms include fever, chills, malaise, and sometimes headache or myalgia, typically occurring within a few hours of transfusion.
FNHTR is characterized by a mild fever and chills without evidence of hemolysis, while hemolytic reactions are more severe and may present with hemoglobinuria, jaundice, and significant changes in vital signs.
