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ICD-10 Guide
ICD-10 CodesR53.82

R53.82

Chronic fatigue, unspecified

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 R53.82 is a billable code used to indicate a diagnosis of chronic fatigue, unspecified.

Key Diagnostic Point:

Chronic fatigue, unspecified (R53.82) is characterized by persistent and debilitating fatigue that lasts for six months or longer and is not attributable to any underlying medical condition. Patients may report a significant decrease in energy levels, difficulty concentrating, sleep disturbances, and a general sense of malaise. This condition can severely impact daily functioning and quality of life. The fatigue experienced is often disproportionate to any recent exertion and is not relieved by rest. It is essential to note that chronic fatigue can be a symptom of various underlying disorders, including autoimmune diseases, endocrine disorders, and psychiatric conditions. Therefore, a thorough clinical evaluation is necessary to rule out other potential causes before assigning this diagnosis. The unspecified nature of this code indicates that the clinician has not identified a specific etiology for the fatigue, which can complicate treatment and management strategies.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Vague nature of the diagnosis can lead to misinterpretation.
  • Requires comprehensive documentation to support the diagnosis.
  • Potential overlap with other fatigue-related codes.
  • Need for thorough differential diagnosis to rule out other conditions.

Audit Risk Factors

  • Insufficient documentation to support the diagnosis of chronic fatigue.
  • Failure to rule out other potential causes of fatigue.
  • Inconsistent use of the code across different encounters.
  • Lack of follow-up documentation to assess the patient's progress.

Specialty Focus

Medical Specialties

Internal Medicine

Documentation Requirements

Detailed patient history, physical examination findings, and any relevant lab results must be documented to support the diagnosis of chronic fatigue.

Common Clinical Scenarios

Patients presenting with fatigue as a primary complaint, often accompanied by other symptoms such as sleep disturbances or cognitive difficulties.

Billing Considerations

Consideration of comorbid conditions such as depression or anxiety that may contribute to fatigue.

Emergency Medicine

Documentation Requirements

Acute care documentation must include a thorough assessment of vital signs, mental status, and any immediate interventions taken.

Common Clinical Scenarios

Patients presenting to the emergency department with acute fatigue, possibly due to dehydration, infection, or other acute illnesses.

Billing Considerations

Rapid assessment to rule out life-threatening conditions that may present with fatigue.

Coding Guidelines

Inclusion Criteria

Use R53.82 When
  • According to ICD
  • 10 coding guidelines, R53
  • 82 should be used when chronic fatigue is documented without a specified cause
  • Coders should ensure that all relevant clinical information is captured to support the diagnosis

Exclusion Criteria

Do NOT use R53.82 When
No specific exclusions found.

Related CPT Codes

99213CPT Code

Established patient office visit, Level 3

Clinical Scenario

Used for follow-up visits for patients with chronic fatigue.

Documentation Requirements

Document the patient's history, examination findings, and any changes in treatment.

Specialty Considerations

Internal medicine may require more detailed documentation compared to other specialties.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of chronic fatigue, but it has also increased the need for detailed documentation to support the diagnosis.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of chronic fatigue, but it has also increased the need for detailed documentation to support the diagnosis.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of chronic fatigue, but it has also increased the need for detailed documentation to support the diagnosis.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the difference between R53.82 and R53.81?

R53.82 is used for chronic fatigue without a specified cause, while R53.81 is specifically for chronic fatigue syndrome, which has defined diagnostic criteria.