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v1.0.0
ICD-10 Guide
ICD-10 CodesR76.0

R76.0

Raised antibody titer

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 R76.0 is a billable code used to indicate a diagnosis of raised antibody titer.

Key Diagnostic Point:

Raised antibody titer refers to an elevated level of antibodies in the blood, which may indicate an immune response to an infection, vaccination, or autoimmune condition. This finding is often identified through serological testing, where specific antibodies are measured to determine the presence of an immune response. Elevated titers can be associated with various conditions, including viral infections (such as hepatitis or HIV), bacterial infections (like syphilis), and autoimmune diseases (such as lupus or rheumatoid arthritis). The clinical significance of a raised antibody titer depends on the context of the patient's symptoms, history, and other laboratory findings. It is essential for healthcare providers to interpret these results in conjunction with clinical findings to arrive at a proper diagnosis and treatment plan. In some cases, a raised titer may not indicate an active disease but rather a past infection or vaccination response, necessitating careful evaluation of the patient's overall clinical picture.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in antibody response among individuals
  • Need for correlation with clinical symptoms
  • Potential for multiple underlying causes
  • Interpretation of serological tests can be complex

Audit Risk Factors

  • Inadequate documentation of clinical correlation
  • Misinterpretation of serological test results
  • Failure to document the reason for testing
  • Coding without supporting clinical evidence

Specialty Focus

Medical Specialties

Internal Medicine

Documentation Requirements

Documentation should include the reason for testing, clinical symptoms, and any relevant history of infections or vaccinations.

Common Clinical Scenarios

Patients presenting with unexplained fatigue, fever, or joint pain may undergo antibody testing to rule out infections or autoimmune disorders.

Billing Considerations

Ensure that the clinical context is well-documented to support the raised titer finding.

Emergency Medicine

Documentation Requirements

Acute care documentation should include the patient's presenting symptoms, any immediate interventions, and the rationale for antibody testing.

Common Clinical Scenarios

Patients with acute febrile illness may be tested for raised antibody titers to identify infectious causes.

Billing Considerations

In emergency settings, rapid interpretation of results is crucial, and documentation should reflect the urgency of the clinical situation.

Coding Guidelines

Inclusion Criteria

Use R76.0 When
  • Follow official ICD
  • CM coding guidelines, ensuring that the raised antibody titer is documented with appropriate clinical context
  • Use additional codes to specify underlying conditions when applicable

Exclusion Criteria

Do NOT use R76.0 When
No specific exclusions found.

Related CPT Codes

86701CPT Code

Antibody test for HIV

Clinical Scenario

Used when testing for raised antibody titers in suspected HIV cases.

Documentation Requirements

Document patient history, risk factors, and reason for testing.

Specialty Considerations

In infectious disease specialties, ensure comprehensive documentation of risk factors.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of raised antibody titers, improving the ability to capture clinical nuances and support better patient care.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of raised antibody titers, improving the ability to capture clinical nuances and support better patient care.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of raised antibody titers, improving the ability to capture clinical nuances and support better patient care.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What does a raised antibody titer indicate?

A raised antibody titer indicates that the immune system has responded to an antigen, which could be due to an active infection, a past infection, or a vaccination.

How should raised antibody titers be documented?

Documentation should include the reason for testing, the specific antibodies tested, and any relevant clinical symptoms or history.