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v1.0.0
ICD-10 Guide
ICD-10 CodesR78.81

R78.81

Bacteremia

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 R78.81 is a billable code used to indicate a diagnosis of bacteremia.

Key Diagnostic Point:

Bacteremia refers to the presence of bacteria in the bloodstream, which can lead to serious infections and systemic inflammatory responses. It is often a sign of an underlying infection that may not be localized, such as pneumonia, urinary tract infections, or skin infections. Symptoms may include fever, chills, tachycardia, and hypotension, which can progress to septic shock if not promptly treated. Laboratory findings typically include positive blood cultures, which confirm the presence of bacteria. The clinical context of bacteremia is critical, as it can indicate severe illness and requires immediate medical intervention. The condition can arise from various sources, including surgical procedures, intravenous drug use, or infections that breach the body's barriers. Accurate diagnosis and timely treatment are essential to prevent complications such as sepsis or organ failure.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between bacteremia and other similar conditions like sepsis.
  • Understanding the clinical context and underlying causes.
  • Interpreting laboratory results accurately.
  • Documenting the source of infection when known.

Audit Risk Factors

  • Inadequate documentation of the source of bacteremia.
  • Failure to link bacteremia to an underlying condition.
  • Misinterpretation of laboratory results.
  • Inconsistent coding of associated symptoms.

Specialty Focus

Medical Specialties

Internal Medicine

Documentation Requirements

Detailed documentation of patient history, clinical findings, and laboratory results is essential. The source of bacteremia should be identified when possible.

Common Clinical Scenarios

Patients presenting with fever and chills, suspected infections, or those with chronic illnesses requiring hospitalization.

Billing Considerations

Consider the patient's overall clinical picture, including comorbidities and potential sources of infection.

Emergency Medicine

Documentation Requirements

Acute care documentation must include vital signs, initial assessment findings, and any interventions performed.

Common Clinical Scenarios

Patients presenting with septic shock, altered mental status, or severe infections requiring immediate intervention.

Billing Considerations

Rapid assessment and documentation are crucial, as timely treatment can significantly impact patient outcomes.

Coding Guidelines

Inclusion Criteria

Use R78.81 When
  • Follow official ICD
  • CM coding guidelines, ensuring that bacteremia is coded only when confirmed by laboratory results
  • Document the clinical context and any associated conditions

Exclusion Criteria

Do NOT use R78.81 When
No specific exclusions found.

Related CPT Codes

87040CPT Code

Culture, bacterial, any source, aerobic, with isolation and presumptive identification of isolates.

Clinical Scenario

Used when blood cultures are performed to confirm bacteremia.

Documentation Requirements

Document the reason for the culture and the clinical findings leading to the test.

Specialty Considerations

Ensure that the culture results are linked to the diagnosis of bacteremia.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of bacteremia, improving the accuracy of data collection and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of bacteremia, improving the accuracy of data collection and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the difference between bacteremia and sepsis?

Bacteremia refers specifically to the presence of bacteria in the bloodstream, while sepsis is a systemic inflammatory response to infection that can occur as a result of bacteremia.