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ICD-10 Guide
ICD-10 CodesR82.1

R82.1

Myoglobinuria

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 R82.1 is a billable code used to indicate a diagnosis of myoglobinuria.

Key Diagnostic Point:

Myoglobinuria is a condition characterized by the presence of myoglobin in the urine, which can occur due to muscle injury or breakdown. Myoglobin is a protein found in muscle tissue that carries oxygen. When muscle cells are damaged, myoglobin is released into the bloodstream and subsequently filtered by the kidneys into the urine. Clinically, myoglobinuria may present with dark, tea-colored urine, muscle pain, weakness, and swelling. It is often associated with conditions such as rhabdomyolysis, which can result from trauma, extreme physical exertion, or certain medications. Laboratory findings typically include elevated serum creatine kinase (CK) levels, and urinalysis may show positive results for blood without red blood cells, indicating myoglobin presence. Prompt recognition and management are crucial to prevent complications such as acute kidney injury, which can arise from the nephrotoxic effects of myoglobin.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating myoglobinuria from hematuria
  • Understanding underlying causes such as rhabdomyolysis
  • Interpreting laboratory results accurately
  • Recognizing associated symptoms and complications

Audit Risk Factors

  • Inadequate documentation of muscle injury or trauma
  • Failure to link myoglobinuria to the underlying cause
  • Misinterpretation of laboratory results
  • Inconsistent coding of associated conditions

Specialty Focus

Medical Specialties

Internal Medicine

Documentation Requirements

Detailed history of muscle symptoms, laboratory findings, and treatment plans.

Common Clinical Scenarios

Patients presenting with muscle pain and dark urine after strenuous exercise.

Billing Considerations

Ensure comprehensive documentation of all contributing factors to muscle injury.

Emergency Medicine

Documentation Requirements

Acute assessment of symptoms, rapid laboratory testing results, and immediate management plans.

Common Clinical Scenarios

Patients with acute muscle trauma or exertional rhabdomyolysis presenting to the ER.

Billing Considerations

Document the urgency of the situation and any interventions performed.

Coding Guidelines

Inclusion Criteria

Use R82.1 When
  • Follow official ICD
  • CM guidelines for coding symptoms and abnormal findings, ensuring that the underlying cause is documented when applicable

Exclusion Criteria

Do NOT use R82.1 When
No specific exclusions found.

Related CPT Codes

80053CPT Code

Comprehensive Metabolic Panel

Clinical Scenario

Used to assess kidney function and electrolyte levels in patients with myoglobinuria.

Documentation Requirements

Document the rationale for ordering the panel and any abnormal findings.

Specialty Considerations

Internal medicine and emergency medicine may require different levels of detail in documentation.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of myoglobinuria, improving the accuracy of data collection and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of myoglobinuria, improving the accuracy of data collection and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common causes of myoglobinuria?

Common causes include rhabdomyolysis due to trauma, extreme physical exertion, certain medications, and metabolic disorders.

How can myoglobinuria be differentiated from hematuria?

Myoglobinuria typically presents with dark urine but without red blood cells on urinalysis, while hematuria shows red blood cells in the urine.