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ICD-10 Guide
ICD-10 CodesZ28.03

Z28.03

Immunization not carried out because of immune compromised state of patient

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/12/2025

Code Description

ICD-10 Z28.03 is a billable code used to indicate a diagnosis of immunization not carried out because of immune compromised state of patient.

Key Diagnostic Point:

Z28.03 is used when a patient is unable to receive immunizations due to an immune compromised state, which may arise from conditions such as HIV/AIDS, cancer treatments, organ transplants, or autoimmune diseases. This code highlights the importance of understanding social determinants of health, as factors like access to healthcare, socioeconomic status, and education can influence a patient's ability to receive preventive care. Preventive measures, including vaccinations, are crucial for this population to avoid infections that could exacerbate their condition. Coders must ensure that documentation reflects the patient's immune status and the rationale for not administering vaccines, as this impacts both clinical care and public health strategies aimed at protecting vulnerable populations.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Requires detailed documentation of the patient's immune status.
  • Involves understanding of various underlying conditions that may compromise immunity.
  • Needs clear communication between healthcare providers regarding vaccination risks.
  • May require additional codes for underlying conditions affecting immunity.

Audit Risk Factors

  • Inadequate documentation of the immune compromised state.
  • Failure to link Z28.03 with appropriate underlying condition codes.
  • Lack of clarity in the rationale for not immunizing.
  • Inconsistent coding practices across different providers.

Specialty Focus

Medical Specialties

Primary Care

Documentation Requirements

Documentation must include the patient's immune status, rationale for not immunizing, and any discussions with the patient regarding vaccination risks.

Common Clinical Scenarios

Routine checkups where immunization is discussed, follow-ups for patients with chronic conditions, and aftercare for patients recovering from immunosuppressive treatments.

Billing Considerations

Consideration of social determinants such as access to healthcare, education about immunization, and the patient's support system.

Public Health

Documentation Requirements

Documentation should include population-level data on immunization rates among immune compromised individuals and tracking of health outcomes.

Common Clinical Scenarios

Epidemiological studies assessing the impact of vaccination on public health, outreach programs targeting immune compromised populations.

Billing Considerations

Focus on health equity and addressing barriers to vaccination in vulnerable populations.

Coding Guidelines

Inclusion Criteria

Use Z28.03 When
  • Z codes should be used when a patient is not receiving care due to specific circumstances
  • 03 should be sequenced appropriately, often following the primary diagnosis code that explains the immune compromised state
  • Payer requirements may vary, so coders should verify specific guidelines for immunization
  • related claims

Exclusion Criteria

Do NOT use Z28.03 When
No specific exclusions found.

Related CPT Codes

90460CPT Code

Immunization administration

Clinical Scenario

Used when administering vaccines to patients who are not immune compromised.

Documentation Requirements

Documentation of the vaccine administered and the patient's immunization history.

Specialty Considerations

Primary care providers should ensure that immunization records are up to date.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has improved specificity in coding for reasons behind immunization deferrals, allowing for better tracking and management of vulnerable populations.

ICD-9 vs ICD-10

The transition to ICD-10 has improved specificity in coding for reasons behind immunization deferrals, allowing for better tracking and management of vulnerable populations.

Reimbursement & Billing Impact

The transition to ICD-10 has improved specificity in coding for reasons behind immunization deferrals, allowing for better tracking and management of vulnerable populations.

Resources

Clinical References

  • •
    CDC Immunization Guidelines

Coding & Billing References

  • •
    CDC Immunization Guidelines

Frequently Asked Questions

What documentation is required to support the use of Z28.03?

Documentation must include the patient's immune status, the specific condition causing the immune compromise, and the rationale for not administering vaccines. This ensures compliance with coding guidelines and supports the clinical decision-making process.