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v1.0.0
ICD-10 Guide
DiagnosesAbnormal Hemoglobin

Abnormal Hemoglobin

ICD-10 Coding for Abnormal Hemoglobin(D58.2, D64.9)

PRIMARY SPECIALTYHematology
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Abnormal Hemoglobin?
Essential facts and insights about Abnormal Hemoglobin

Key Clinical Considerations:

  • Presence of abnormal hemoglobin levels in blood test results
  • Symptoms such as fatigue, weakness, or shortness of breath
  • Family history of hemoglobinopathies

Clinical Information

Clinical Criteria & Documentation Requirements

  • Detailed description of patient's symptoms
  • Results of laboratory tests indicating abnormal hemoglobin levels
  • Record of family history of hemoglobin disorders

Coding Guidelines

Usage Guidelines & Examples

  • D58.2 is used for hereditary persistence of fetal hemoglobin, while D64.9 is a non-specific code for anemia, unspecified
  • D64.9 should only be used when there is insufficient detail to code the condition more specifically

Code Exclusions

Important Exclusions

  • Conditions such as sickle cell disorders (D57.-)
  • Thalassemia (D56.-)

Related ICD-10 Codes

Primary Codes
D58.2
Hereditary persistence of fetal hemoglobin
D64.9
Anemia, unspecified
Ancillary Codes
R79.89
Differential Codes
D56.1
D63.1
D63.1
when anemia is due to a chronic condition.

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Hematology

Specialty Applications

  • Patients with hereditary persistence of fetal hemoglobin
  • Patients with anemia where the specific type is not known

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Template 1

Patient presents with symptoms consistent with abnormal hemoglobin, including [detail symptoms].

Template 2

Laboratory tests confirm the presence of abnormal hemoglobin levels in the patient.

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

What is abnormal hemoglobin?

Abnormal hemoglobin refers to a group of genetic disorders that affect the structure, function, or production of hemoglobin.

When should this code be used?

These codes should be used when a patient has been diagnosed with abnormal hemoglobin levels or anemia, and the specific type of anemia is not known.