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ICD-10 Guide
DiagnosesAmphetamine Use

Amphetamine Use

ICD-10 Coding for Amphetamine Use(F15.10, F15.20)

PRIMARY SPECIALTYEmergency Medicine
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Amphetamine Use?
Essential facts and insights about Amphetamine Use

Key Clinical Considerations:

  • Presence of amphetamine use disorder symptoms such as increased energy, decreased appetite, and euphoria.
  • Laboratory findings may include urine drug screening positive for amphetamines.
  • Physical examination may reveal increased heart rate, elevated blood pressure, and dilated pupils.
  • Imaging findings are generally not applicable but may include brain imaging in cases of severe complications.
  • Severity criteria include the number of symptoms present and the impact on daily functioning.

Clinical Information

Clinical Criteria & Documentation Requirements

  • Documentation must include the patient's history of amphetamine use, including duration and quantity.
  • Specific terminology such as 'amphetamine use disorder' or 'amphetamine intoxication' must be used.
  • Examples include noting the patient's reported symptoms and any observed physical signs.
  • Medical necessity must be established through documentation of the impact of amphetamine use on health.
  • Quality measures may include tracking treatment outcomes and follow-up care.

Coding Guidelines

Usage Guidelines & Examples

  • Use F15.10 for amphetamine use disorder, uncomplicated, and F15.20 for amphetamine use disorder, in remission.
  • Do not use these codes for non-specific stimulant use or for other substance use disorders.
  • F15.21 (amphetamine use disorder, mild) and F15.22 (moderate) are related codes that specify severity.
  • Common errors include misclassifying the severity of the disorder; ensure documentation supports the chosen code.
  • In complex cases, consider the patient's overall substance use history and any co-occurring disorders.

Code Exclusions

Important Exclusions

  • Excludes other stimulant use disorders such as cocaine or methamphetamine use.
  • Alternative codes for excluded conditions include F14 (Cocaine related disorders) for cocaine use.
  • Conditions are excluded to ensure accurate representation of the specific substance involved.
  • Common mistakes include using amphetamine codes for patients with primary alcohol use disorders.
  • Related but distinct conditions include stimulant-induced psychotic disorder.

Related ICD-10 Codes

Primary Codes
F15.10
Amphetamine use disorder, uncomplicated
F15.20
Amphetamine use disorder, in remission
Differential Codes
F15.20
F15.10

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Emergency Medicine

Specialty Applications

  • Applies to patients diagnosed with amphetamine use disorder or those presenting with symptoms of intoxication.
  • Patient populations include adolescents and adults, particularly those with a history of substance use.
  • Clinical settings include emergency departments, outpatient clinics, and inpatient psychiatric units.
  • Specialty-specific applications may involve addiction medicine and psychiatry.
  • Treatment contexts include detoxification, rehabilitation, and ongoing management of substance use disorders.

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Template 1

Template: 'Patient diagnosed with amphetamine use disorder based on clinical findings of increased energy and decreased appetite.'

Template 2

Template: 'Clinical presentation consistent with amphetamine use disorder including euphoria and increased heart rate.'

Template 3

Template: 'Diagnostic criteria for amphetamine use disorder met as evidenced by reported symptoms and positive drug screen.'

Template 4

Template: 'Treatment plan initiated for amphetamine use disorder with referral to substance use counseling.'

Template 5

Template: 'Follow-up care for amphetamine use disorder including monitoring for relapse and ongoing support.'

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

What documentation is required for this diagnosis?

Detailed documentation of the patient's substance use history, symptoms, and any treatment plans.

How does this differ from similar diagnoses?

Amphetamine use disorder is specifically related to amphetamines, while other stimulant disorders pertain to different substances.

What are common billing considerations?

Ensure that the diagnosis is supported by clinical documentation to optimize reimbursement.

What procedures are typically associated?

Related CPT codes may include those for substance use assessments and counseling.

Are there any quality reporting implications?

Quality measures may include tracking treatment adherence and patient outcomes related to substance use.