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v1.0.0
ICD-10 Guide
DiagnosesAmphetamine Use Disorder

Amphetamine Use Disorder

ICD-10 Coding for Amphetamine Use Disorder(F15.10, F15.20)

PRIMARY SPECIALTYEmergency Medicine
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Amphetamine Use Disorder?
Essential facts and insights about Amphetamine Use Disorder

Key Clinical Considerations:

  • A pattern of amphetamine use leading to clinically significant impairment or distress, as manifested by at least two of the following occurring within a 12-month period: tolerance, withdrawal, taking larger amounts over a longer period than intended, unsuccessful efforts to cut down or control use, a great deal of time spent in activities necessary to obtain, use, or recover from the effects of amphetamines, craving or a strong desire to use amphetamines, recurrent use resulting in a failure to fulfill major role obligations at work, school, or home, continued use despite having persistent or recurrent social or interpersonal problems caused or exacerbated by the effects of amphetamines, important social, occupational, or recreational activities are given up or reduced because of use, and recurrent use in situations in which it is physically hazardous.
  • No specific laboratory findings are required for diagnosis; however, toxicology screens may be used to confirm amphetamine presence.
  • Physical examination may reveal signs of stimulant use such as increased heart rate, elevated blood pressure, dilated pupils, and potential signs of withdrawal.
  • Imaging studies are not typically required for diagnosis but may be used to assess any complications related to amphetamine use.
  • Severity is classified as mild (2-3 criteria met), moderate (4-5 criteria met), or severe (6 or more criteria met).

Clinical Information

Clinical Criteria & Documentation Requirements

  • Documentation must include a comprehensive history of substance use, including frequency, quantity, and context of amphetamine use.
  • Specific terminology such as 'amphetamine use disorder' and severity level must be clearly documented.
  • Examples include: 'Patient presents with amphetamine use disorder, moderate severity, as evidenced by tolerance and withdrawal symptoms.'
  • Medical necessity must be established through documentation of the impact of amphetamine use on the patient's functioning.
  • Quality measures may include documentation of screening for substance use disorders and follow-up care plans.

Coding Guidelines

Usage Guidelines & Examples

  • Use F15.10 for amphetamine use disorder, uncomplicated, and F15.20 for amphetamine use disorder, in remission.
  • Do not use these codes for patients with other substance use disorders unless amphetamine use disorder is also present.
  • Related codes include F15.21 for amphetamine use disorder with withdrawal and F15.22 for amphetamine use disorder with intoxication.
  • Common errors include misclassifying the severity of the disorder or failing to document the specific criteria met.
  • In complex cases, ensure all criteria are documented and consider consulting DSM-5 guidelines for clarification.

Code Exclusions

Important Exclusions

  • Excludes individuals with primary psychotic disorders or mood disorders without substance use.
  • Alternative codes for excluded conditions include F20 for schizophrenia or F32 for major depressive disorder.
  • Conditions are excluded to ensure accurate diagnosis and treatment planning.
  • Common mistakes include misdiagnosing amphetamine use disorder in patients with primary psychiatric conditions.
  • Related but distinct conditions include cocaine use disorder and other stimulant use disorders.

Related ICD-10 Codes

Primary Codes
F15.10
Amphetamine use disorder, uncomplicated
F15.20
Amphetamine use disorder, in remission
Differential Codes
F15.20
F15.10

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Emergency Medicine

Specialty Applications

  • Applies to individuals diagnosed with amphetamine use disorder as per DSM-5 criteria.
  • Patient populations include adolescents and adults, particularly those with a history of substance use.
  • Clinical settings include emergency departments, inpatient rehabilitation, and outpatient treatment facilities.
  • Specialty-specific applications may involve addiction medicine, psychiatry, and emergency medicine.
  • Treatment contexts include detoxification, rehabilitation, and ongoing outpatient therapy.

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Template 1

Template: 'Patient diagnosed with amphetamine use disorder based on clinical findings of tolerance and withdrawal.'

Template 2

Template: 'Clinical presentation consistent with amphetamine use disorder including increased tolerance and social impairment.'

Template 3

Template: 'Diagnostic criteria for amphetamine use disorder met as evidenced by recurrent use and failure to fulfill obligations.'

Template 4

Template: 'Treatment plan initiated for amphetamine use disorder with counseling and monitoring for withdrawal symptoms.'

Template 5

Template: 'Follow-up care for amphetamine use disorder including regular assessments of substance use and mental health status.'

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

What documentation is required for this diagnosis?

Detailed documentation of the patient's substance use history, clinical symptoms, and severity assessment.

How does this differ from similar diagnoses?

Amphetamine use disorder is specifically related to the use of amphetamines, while other disorders may involve different substances.

What are common billing considerations?

Ensure accurate coding based on documented severity and associated conditions to optimize reimbursement.

What procedures are typically associated?

Related CPT codes may include substance use screening and counseling services.

Are there any quality reporting implications?

Quality measures may include screening rates for substance use disorders and follow-up care documentation.