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v1.0.0
ICD-10 Guide
DiagnosesHerpes Simplex Virus

Herpes Simplex Virus

ICD-10 Coding for Herpes Simplex Virus(B00.0, B00.1)

PRIMARY SPECIALTYDentistry
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Herpes Simplex Virus?
Essential facts and insights about Herpes Simplex Virus

Key Clinical Considerations:

  • Painful vesicular lesions on the oral mucosa and lips
  • PCR testing for HSV DNA, viral culture, or serological tests for HSV antibodies
  • Erythema, swelling, and ulceration in the affected areas

Clinical Information

Clinical Criteria & Documentation Requirements

  • Patient history of previous outbreaks, current symptoms, and duration
  • Use of specific ICD-10 codes for herpes simplex virus
  • Examples include noting the location of lesions and patient response to treatment

Coding Guidelines

Usage Guidelines & Examples

  • Follow guidelines for distinguishing between oral and genital herpes
  • Common errors include using outdated codes or incorrect site-specific codes

Code Exclusions

Important Exclusions

  • Other viral infections of the oral cavity
  • Alternative codes for herpes zoster or other herpes viruses

Related ICD-10 Codes

Primary Codes
B00.1
Herpes simplex labialis
B00.2
Herpes simplex gingivostomatitis
Ancillary Codes
G05.1
B00.4
for HSV encephalitis.
Differential Codes
B02.0
B08.5

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Dentistry

Specialty Applications

  • Patients with recurrent oral herpes outbreaks
  • Dental clinics and oral health specialists

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

Documentation requirements?

Include patient history, clinical findings, and treatment plan.

Billing considerations?

Ensure correct ICD-10 codes are used to avoid claim denials.