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v1.0.0
ICD-10 Guide
DiagnosesMajor Recurrent Depression

Major Recurrent Depression

ICD-10 Coding for Major Recurrent Depression(F33.0, F33.1, F33.2, F33.3, F33.41, F33.42)

PRIMARY SPECIALTYPsychiatry
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Major Recurrent Depression?
Essential facts and insights about Major Recurrent Depression

Key Clinical Considerations:

  • Depressed mood most of the day, nearly every day
  • Loss of interest or pleasure in most activities
  • Significant weight loss or gain, or decrease/increase in appetite
  • Insomnia or hypersomnia
  • Psychomotor agitation or retardation
  • Fatigue or loss of energy
  • Feelings of worthlessness or excessive guilt
  • Diminished ability to think or concentrate
  • Recurrent thoughts of death or suicidal ideation

Clinical Information

Clinical Criteria & Documentation Requirements

  • Patient history including duration and severity of symptoms
  • Assessment of functional impairment
  • Treatment history and response to previous interventions
  • Specific terminology such as 'Major Depressive Episode' or 'Recurrent Major Depression'
  • Examples of documentation: 'Patient reports feeling hopeless for the past 3 months.'

Coding Guidelines

Usage Guidelines & Examples

  • Usage guidelines: Use F33 codes for recurrent episodes; differentiate by severity.
  • Common errors: Misclassifying as single episode or failing to document recurrence.

Code Exclusions

Important Exclusions

  • Excludes conditions such as bipolar disorder and adjustment disorders with depressed mood
  • Alternative codes may include F32 for single episodes of depression.

Related ICD-10 Codes

Primary Codes
F33.1
Major depressive disorder, recurrent, moderate
F33.2
Major depressive disorder, recurrent, severe
Ancillary Codes
Z63.5
F41.8
Differential Codes
F34.1
F43.21
F33.3
F33.3
from
F33.2
.
F33.2
F33.2
from
F33.3
.

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Psychiatry

Specialty Applications

  • Adult and adolescent populations
  • Outpatient and inpatient psychiatric settings

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

Documentation requirements?

Include detailed patient history, symptom duration, and treatment response.

Billing considerations?

Ensure accurate coding to reflect severity and recurrence for appropriate reimbursement.