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ICD-10 Guide
DiagnosesMixed Anxiety And Depressive Disorder

Mixed Anxiety And Depressive Disorder

ICD-10 Coding for Mixed Anxiety and Depressive Disorder(F41.2)

PRIMARY SPECIALTYPsychiatry
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Mixed Anxiety And Depressive Disorder?
Essential facts and insights about Mixed Anxiety and Depressive Disorder

Key Clinical Considerations:

  • Persistent feelings of anxiety and depression lasting for at least 6 months
  • Symptoms include excessive worry, restlessness, fatigue, difficulty concentrating, and feelings of hopelessness
  • No specific diagnostic tests; diagnosis based on clinical assessment and patient history
  • Physical exam may reveal signs of anxiety (e.g., increased heart rate, sweating) and depressive symptoms (e.g., changes in appetite or sleep patterns)

Clinical Information

Clinical Criteria & Documentation Requirements

  • Document patient's history of symptoms, duration, and impact on daily functioning
  • Use specific coding terminology such as 'mixed anxiety and depressive disorder' or 'comorbid anxiety and depression'
  • Examples include detailed accounts of symptom severity, treatment response, and any co-occurring conditions

Coding Guidelines

Usage Guidelines & Examples

  • Usage guidelines emphasize the need for clear documentation of both anxiety and depressive symptoms.
  • Common errors include misclassifying the disorder as solely anxiety or depression without acknowledging the mixed nature.

Code Exclusions

Important Exclusions

  • Excludes conditions such as generalized anxiety disorder (GAD) and major depressive disorder (MDD) when diagnosed separately
  • Alternative codes may include F41.1 (Generalized anxiety disorder) or F33.2 (Major depressive disorder, recurrent, severe)

Related ICD-10 Codes

Primary Codes
F41.8
Other specified anxiety disorders
F33.1
Major depressive disorder, recurrent, moderate
Differential Codes
F32.9
F41.9

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Psychiatry

Specialty Applications

  • Adults and adolescents experiencing both anxiety and depressive symptoms
  • Clinical settings such as outpatient psychiatry, inpatient mental health facilities, and primary care

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

Documentation requirements?

Include a thorough assessment of symptoms, duration, and functional impairment.

Billing considerations?

Ensure accurate coding to reflect the complexity of the disorder for appropriate reimbursement.