ICD-10 Guide

Mixed Hyperlipidemia

ICD-10 Coding for Mixed Hyperlipidemia(E78.2)

PRIMARY SPECIALTYPrimary Care

COMPLEXITYHigh

LAST UPDATED09/15/2025

Sam Tuffun, PT, DPT

Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Mixed Hyperlipidemia?

Essential facts and insights about Mixed Hyperlipidemia

Key Clinical Considerations:

Elevated total cholesterol levels
Elevated triglycerides
Low HDL cholesterol levels
Possible symptoms include xanthomas or pancreatitis

Clinical Information

Clinical Criteria & Documentation Requirements

Patient history of lipid levels
Results of lipid panel tests
Family history of hyperlipidemia
Lifestyle factors (diet, exercise)

Coding Guidelines

Usage Guidelines & Examples

Follow guidelines for coding mixed hyperlipidemia versus other types of dyslipidemia.
Common errors include misclassifying mixed hyperlipidemia as primary or secondary dyslipidemia.

Code Exclusions

Important Exclusions

Familial hyperlipidemia
Secondary causes of hyperlipidemia such as diabetes or hypothyroidism

Specialty Focus

Primary Specialty

Primary Care

Specialty Applications

Adults with risk factors for cardiovascular disease
Primary care settings, endocrinology, and cardiology

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

Comprehensive clinical documentation
Accurate code selection based on clinical criteria
Proper exclusion considerations
Specialty-specific coding guidelines

Documentation

Documentation Templates

Billing Information

Billing Considerations

Ensure proper documentation for billing
Verify code specificity requirements
Check for any additional codes needed
Review payer-specific guidelines

Common Issues

Insufficient clinical documentation
Incorrect code selection
Missing supporting diagnoses
Timing and frequency documentation

Frequently Asked Questions

What are the documentation requirements?

Document lipid panel results, patient history, and any related symptoms.

What are the billing considerations?

Ensure accurate coding based on lipid panel results and associated conditions.

Mixed Hyperlipidemia

Diagnosis Overview

Key Clinical Considerations:

Clinical Information

Clinical Criteria & Documentation Requirements

Coding Guidelines

Usage Guidelines & Examples

Code Exclusions

Important Exclusions

Related ICD-10 Codes

Related CPT Codes

Specialty Focus

Primary Specialty

Specialty Applications

Coding Complexity

Documentation

Documentation Templates

Billing Information

Billing Considerations

Common Issues

Frequently Asked Questions

What are the documentation requirements?

What are the billing considerations?

Mixed Hyperlipidemia

Diagnosis Overview

Key Clinical Considerations:

Clinical Information

Clinical Criteria & Documentation Requirements

Coding Guidelines

Usage Guidelines & Examples

Code Exclusions

Important Exclusions

Related ICD-10 Codes

Related CPT Codes

Specialty Focus

Primary Specialty

Specialty Applications

Coding Complexity

Documentation

Documentation Templates

Billing Information

Billing Considerations

Common Issues

Frequently Asked Questions

What are the documentation requirements?

What are the billing considerations?