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ICD-10 Guide
DiagnosesMultiple Thyroid Nodule

Multiple Thyroid Nodule

ICD-10 Coding for Multiple Thyroid Nodules(E04.2, E05.20)

PRIMARY SPECIALTYEndocrinology
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Multiple Thyroid Nodule?
Essential facts and insights about Multiple Thyroid Nodules

Key Clinical Considerations:

  • Palpable thyroid nodules
  • Thyroid function tests (TFTs) showing normal TSH levels
  • Ultrasound findings of multiple nodules

Clinical Information

Clinical Criteria & Documentation Requirements

  • Patient history including symptoms and family history of thyroid disease
  • Results of imaging studies (e.g., ultrasound)
  • Thyroid function test results

Coding Guidelines

Usage Guidelines & Examples

  • Follow guidelines for coding multiple nodules versus single nodules.
  • Common errors include misclassifying benign nodules as malignant.

Code Exclusions

Important Exclusions

  • Thyroid carcinoma
  • Single thyroid nodule (E04.1)

Related ICD-10 Codes

Primary Codes
E04.2
Multiple thyroid nodules
Ancillary Codes
E07.8
Differential Codes
E05.20
E04.2

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Endocrinology

Specialty Applications

  • Adults with thyroid nodules
  • Endocrinology clinics and outpatient settings

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

What are the documentation requirements?

Document the size, number, and characteristics of nodules, along with any relevant lab results.

What are the billing considerations?

Ensure accurate coding based on the number of nodules and any associated procedures.