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ICD-10 Guide
DiagnosesRapid Plasma Reagin Test

Rapid Plasma Reagin Test

ICD-10 Coding for Rapid Plasma Reagin Test(A53.9, R76.8)

PRIMARY SPECIALTYInfectious Disease
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Rapid Plasma Reagin Test?
Essential facts and insights about Rapid Plasma Reagin Test

Key Clinical Considerations:

  • Presence of syphilis-related symptoms such as rash, sores, or fever
  • Positive Rapid Plasma Reagin (RPR) test result
  • Physical examination may reveal lesions or systemic symptoms

Clinical Information

Clinical Criteria & Documentation Requirements

  • Patient history including risk factors for syphilis
  • Results of RPR test and any confirmatory tests (e.g., FTA-ABS)
  • Documentation of clinical findings and symptoms

Coding Guidelines

Usage Guidelines & Examples

  • Follow guidelines for coding syphilis based on stage and symptoms.
  • Common errors include using outdated codes or not documenting test results.

Code Exclusions

Important Exclusions

  • Other sexually transmitted infections (STIs) not related to syphilis
  • Alternative codes for non-infectious conditions

Related ICD-10 Codes

Primary Codes
A50.0
Congenital syphilis, early
A53.9
Syphilis, unspecified
Ancillary Codes
B97.89
Differential Codes
R76.8
A53.9

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Infectious Disease

Specialty Applications

  • Individuals at risk for syphilis, including sexually active adults and pregnant women
  • Infectious disease clinics, primary care settings, and sexual health services

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

Documentation requirements?

Document patient history, test results, and clinical findings.

Billing considerations?

Ensure correct ICD codes are used based on test results and clinical presentation.