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v1.0.0
ICD-10 Guide
DiagnosesRecurrent Major Depression

Recurrent Major Depression

ICD-10 Coding for Recurrent Major Depression(F33.0, F33.1, F33.2, F33.3, F33.4)

PRIMARY SPECIALTYPsychiatry
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Recurrent Major Depression?
Essential facts and insights about Recurrent Major Depression

Key Clinical Considerations:

  • Persistent feelings of sadness or low mood lasting for at least two weeks
  • Loss of interest or pleasure in most activities
  • Significant weight loss or gain, or changes in appetite
  • Insomnia or hypersomnia
  • Fatigue or loss of energy
  • Feelings of worthlessness or excessive guilt
  • Difficulty concentrating or making decisions
  • Recurrent thoughts of death or suicidal ideation

Clinical Information

Clinical Criteria & Documentation Requirements

  • Patient history including previous episodes of depression
  • Assessment of severity and duration of symptoms
  • Evidence of functional impairment in daily activities
  • Use of standardized assessment tools (e.g., PHQ-9)
  • Clear documentation of treatment plan and follow-up

Coding Guidelines

Usage Guidelines & Examples

  • Usage guidelines emphasize the importance of specifying the episode severity.
  • Common errors include misclassifying the episode type or failing to document recurrent episodes.

Code Exclusions

Important Exclusions

  • Bipolar disorder (F31)
  • Adjustment disorder with depressed mood (F43.21)
  • Substance-induced mood disorder (F11.3, F12.3, etc.)

Related ICD-10 Codes

Primary Codes
F33.1
Recurrent major depressive disorder, current episode moderate
F33.2
Recurrent major depressive disorder, current episode severe without psychotic features
F33.3
Recurrent major depressive disorder, current episode severe with psychotic features
Ancillary Codes
Z63.0
F41.8
R45.81
F20.81
Z86.59
Differential Codes
F32.0
F32.0
for single episode depression, not recurrent.
F32.1
F32.1
for single episode depression, not recurrent.
F32.2
F32.2
for single episode depression, not recurrent.
F32.3
F32.3
for single episode depression, not recurrent.
F32.4
F32.4
for single episode depression, not recurrent.

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Psychiatry

Specialty Applications

  • Adults and adolescents with a history of major depressive episodes
  • Outpatient psychiatric settings and inpatient mental health facilities

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

What are the documentation requirements?

Documentation must include a detailed history, symptom assessment, and treatment plan.

What are the billing considerations?

Ensure accurate coding based on severity and episode type to avoid claim denials.