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v1.0.0
ICD-10 Guide
ICD-10 CodesA04.1

A04.1

Enterotoxigenic Escherichia coli infection

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/04/2025

Code Description

ICD-10 A04.1 is a billable code used to indicate a diagnosis of enterotoxigenic escherichia coli infection.

Key Diagnostic Point:

Infection caused by enterotoxigenic strains of Escherichia coli, often leading to diarrhea and gastrointestinal distress, commonly associated with traveler's diarrhea.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of symptoms
  • Potential for dehydration

Audit Risk Factors

    Specialty Focus

    Medical Specialties

    Infectious Disease

    Documentation Requirements

    Detailed patient history, including travel and exposure history.

    Common Clinical Scenarios

    Patients presenting with acute diarrhea after travel to endemic areas.

    Billing Considerations

    Consideration of co-infections and antibiotic resistance patterns.

    Coding Guidelines

    Inclusion Criteria

    Use A04.1 When
    • Use this code when the infection is confirmed and symptoms are present; ensure to document the travel history

    Exclusion Criteria

    Do NOT use A04.1 When
    No specific exclusions found.

    Related CPT Codes

    87430CPT Code

    Infectious agent detection by nucleic acid (DNA or RNA); enteric pathogens

    Clinical Scenario

    Testing for E. coli in patients with diarrhea.

    Documentation Requirements

    Document symptoms and travel history.

    Specialty Considerations

    Consider testing for other pathogens if symptoms persist.

    ICD-10 Impact

    Diagnostic & Documentation Impact

    Enhanced Specificity

    ICD-10 Improvements

    Accurate coding impacts treatment protocols and tracking of infectious disease outbreaks.

    ICD-9 vs ICD-10

    Accurate coding impacts treatment protocols and tracking of infectious disease outbreaks.

    Reimbursement & Billing Impact

    Accurate coding impacts treatment protocols and tracking of infectious disease outbreaks.

    Resources

    Clinical References

    • •
      CDC Guidelines on E. coli Infections

    Coding & Billing References

    • •
      CDC Guidelines on E. coli Infections

    Frequently Asked Questions

    What are the common symptoms of enterotoxigenic E. coli infection?

    Common symptoms include watery diarrhea, abdominal cramps, nausea, and vomiting.

    How is enterotoxigenic E. coli infection treated?

    Treatment primarily focuses on hydration and electrolyte replacement; antibiotics may be used in severe cases.