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ICD-10 Guide
ICD-10 CodesA52.76

A52.76

Other genitourinary symptomatic late syphilis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A52.76 is a billable code used to indicate a diagnosis of other genitourinary symptomatic late syphilis.

Key Diagnostic Point:

A52.76 refers to a specific manifestation of late syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. Late syphilis can present with various symptoms affecting the genitourinary system, including but not limited to urethritis, genital ulcers, and other symptomatic conditions that may arise as the disease progresses. This stage of syphilis typically occurs years after the initial infection if left untreated. Patients may experience complications such as inflammation, scarring, and potential infertility due to the chronic nature of the infection. Diagnosis is primarily based on serological testing, including non-treponemal tests (e.g., RPR, VDRL) and treponemal tests (e.g., FTA-ABS). Treatment usually involves the administration of benzathine penicillin G, which is effective in eradicating the infection and preventing further complications. It is crucial for healthcare providers to conduct thorough patient histories and sexual health assessments to identify potential contacts for tracing and treatment, as syphilis is highly contagious and can lead to severe health issues if not addressed promptly.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of symptoms that can complicate diagnosis
  • Need for accurate serological testing interpretation
  • Potential for co-infection with other STIs
  • Documentation of patient history and sexual contacts

Audit Risk Factors

  • Inadequate documentation of symptoms
  • Failure to document treatment response
  • Lack of patient follow-up records
  • Improper coding of related conditions

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed patient history, serological test results, treatment plans, and follow-up care.

Common Clinical Scenarios

Patients presenting with genital ulcers, urethritis, or systemic symptoms related to late syphilis.

Billing Considerations

Ensure thorough documentation of sexual history and any co-infections.

Urology

Documentation Requirements

Clinical findings related to genitourinary symptoms, imaging studies, and treatment outcomes.

Common Clinical Scenarios

Patients with urinary symptoms or complications from syphilis affecting the urinary tract.

Billing Considerations

Document any surgical interventions or procedures performed.

Coding Guidelines

Inclusion Criteria

Use A52.76 When
  • According to ICD
  • 10 guidelines, A52
  • 76 should be used when there is clear documentation of genitourinary symptoms associated with late syphilis
  • It is important to ensure that the diagnosis is confirmed through appropriate testing and that any related conditions are also documented

Exclusion Criteria

Do NOT use A52.76 When
No specific exclusions found.

Related CPT Codes

86592CPT Code

Syphilis serology test

Clinical Scenario

Used for screening and diagnosis of syphilis in patients presenting with symptoms.

Documentation Requirements

Document the reason for testing and the results.

Specialty Considerations

Infectious disease specialists should ensure comprehensive testing for co-infections.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of late syphilis manifestations, improving the accuracy of epidemiological data and treatment tracking.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of late syphilis manifestations, improving the accuracy of epidemiological data and treatment tracking.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of late syphilis manifestations, improving the accuracy of epidemiological data and treatment tracking.

Resources

Clinical References

  • •
    CDC Syphilis Treatment Guidelines

Coding & Billing References

  • •
    CDC Syphilis Treatment Guidelines

Frequently Asked Questions

What are the common symptoms of late syphilis?

Common symptoms include genital ulcers, urethritis, and systemic manifestations such as fever and rash. Late syphilis can also lead to serious complications if untreated.