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ICD-10 Guide
ICD-10 CodesA69.22

A69.22

Other neurologic disorders in Lyme disease

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A69.22 is a billable code used to indicate a diagnosis of other neurologic disorders in lyme disease.

Key Diagnostic Point:

A69.22 refers to neurologic manifestations associated with Lyme disease, a tick-borne illness caused by the spirochete Borrelia burgdorferi. This condition can lead to various neurologic disorders, including meningitis, encephalitis, and peripheral neuropathy. The clinical presentation may vary widely, with symptoms such as headache, neck stiffness, cognitive impairment, and radicular pain. Lyme disease is endemic in certain geographic areas, particularly in the northeastern, north-central, and Pacific coastal regions of the United States, as well as parts of Europe and Asia. The diagnosis of neurologic Lyme disease is often made based on clinical findings, serologic testing, and, in some cases, cerebrospinal fluid analysis. Treatment typically involves antibiotics, and early intervention is crucial to prevent long-term complications. Understanding the geographic distribution of Lyme disease is essential for clinicians and coders alike, as it informs the likelihood of encountering this condition in specific patient populations.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of neurologic symptoms that can present
  • Need for differential diagnosis with other neurologic conditions
  • Geographic variability in disease prevalence
  • Potential for co-infection with other tick-borne diseases

Audit Risk Factors

  • Inadequate documentation of neurologic symptoms
  • Failure to document serologic test results
  • Misdiagnosis or coding of similar conditions
  • Lack of clarity in the clinical rationale for diagnosis

Specialty Focus

Medical Specialties

Neurology

Documentation Requirements

Detailed clinical notes on neurologic symptoms, diagnostic tests, and treatment plans.

Common Clinical Scenarios

Patients presenting with headaches, cognitive dysfunction, or neuropathic pain.

Billing Considerations

Neurologists should ensure comprehensive documentation of neurologic assessments and any relevant imaging or lab results.

Infectious Disease

Documentation Requirements

Thorough documentation of exposure history, serologic testing, and treatment response.

Common Clinical Scenarios

Patients with suspected Lyme disease presenting with systemic symptoms and neurologic involvement.

Billing Considerations

Infectious disease specialists should document the geographic exposure and potential co-infections.

Coding Guidelines

Inclusion Criteria

Use A69.22 When
  • According to ICD
  • 10 guidelines, A69
  • 22 should be used when a patient presents with neurologic symptoms directly attributable to Lyme disease
  • Coders must ensure that documentation supports the diagnosis and that other potential causes of neurologic symptoms are ruled out

Exclusion Criteria

Do NOT use A69.22 When
No specific exclusions found.

Related CPT Codes

96372CPT Code

Therapeutic, prophylactic, or diagnostic injection into a major joint or bursa

Clinical Scenario

Used when administering antibiotics for Lyme disease treatment.

Documentation Requirements

Document the indication for injection and the patient's response.

Specialty Considerations

Ensure that the specialty performing the injection is clearly documented.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of Lyme disease and its complications, improving the accuracy of data collection and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of Lyme disease and its complications, improving the accuracy of data collection and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    CDC Lyme Disease Information

Coding & Billing References

  • •
    CDC Lyme Disease Information

Frequently Asked Questions

What are the common neurologic symptoms associated with Lyme disease?

Common neurologic symptoms include headaches, cognitive dysfunction, peripheral neuropathy, and, in severe cases, meningitis or encephalitis.