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ICD-10 Guide
ICD-10 CodesChapter 1: Certain infectious and parasitic diseasesA80.3

A80.3

Billable

Acute poliomyelitis due to poliovirus, vaccine-associated

Chapter 1:Certain infectious and parasitic diseases

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A80.3 is a billable code used to indicate a diagnosis of acute poliomyelitis due to poliovirus, vaccine-associated.

Key Diagnostic Point:

Acute poliomyelitis due to poliovirus, vaccine-associated, refers to a rare neurological condition that can occur following the administration of live attenuated oral poliovirus vaccine (OPV). This condition is characterized by the inflammation of the spinal cord and brain, leading to muscle weakness, paralysis, and other neurological complications. Vaccine-associated poliomyelitis typically arises in individuals who have received the OPV, particularly in immunocompromised patients or those with underlying health conditions that may predispose them to adverse reactions. The clinical presentation may include sudden onset of flaccid paralysis, fever, and muscle weakness, often affecting the lower limbs. Diagnosis is confirmed through clinical evaluation, history of vaccination, and laboratory tests, including viral isolation from stool or cerebrospinal fluid (CSF). It is crucial for healthcare providers to differentiate vaccine-associated poliomyelitis from wild poliovirus infections, as the management and public health implications differ significantly. The incidence of vaccine-associated poliomyelitis has decreased significantly with the global shift towards inactivated poliovirus vaccine (IPV) in many countries, but awareness and accurate coding remain essential for monitoring and epidemiological purposes.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Requires knowledge of vaccination history and its implications.
  • Differentiation from other types of poliomyelitis (wild-type).
  • Need for precise documentation of neurological symptoms.
  • Potential for misclassification with other CNS infections.

Audit Risk Factors

  • Inadequate documentation of vaccination status.
  • Failure to document neurological symptoms accurately.
  • Misclassification with other CNS infections.
  • Lack of follow-up documentation on patient outcomes.

Specialty Focus

Medical Specialties

Neurology

Documentation Requirements

Detailed neurological examination findings, vaccination history, and symptom onset.

Common Clinical Scenarios

Patients presenting with acute flaccid paralysis following OPV administration.

Billing Considerations

Ensure thorough documentation of neurological deficits and any relevant imaging or laboratory results.

Infectious Disease

Documentation Requirements

History of vaccination, laboratory confirmation of poliovirus type, and clinical presentation.

Common Clinical Scenarios

Patients with suspected vaccine-associated poliomyelitis requiring differential diagnosis from other viral infections.

Billing Considerations

Document any immunocompromised status and potential exposure history.

Coding Guidelines

Inclusion Criteria

Use A80.3 When
  • According to ICD
  • 10 coding guidelines, A80
  • 3 should be used when the condition is specifically due to vaccine
  • associated poliovirus
  • It is important to document the vaccination history and any relevant clinical findings

Exclusion Criteria

Do NOT use A80.3 When
  • Exclusion criteria include cases where the poliomyelitis is due to wild poliovirus or other etiologies

Related ICD-10 Codes

Related CPT Codes

87400CPT Code

Infectious agent detection by nucleic acid (DNA or RNA); viral, amplified probe technique

Clinical Scenario

Used for confirming the presence of poliovirus in CSF or stool samples.

Documentation Requirements

Document the reason for testing and the clinical presentation.

Specialty Considerations

Neurology and Infectious Disease specialists should ensure comprehensive documentation of clinical findings.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of vaccine-associated poliomyelitis, improving data accuracy and public health monitoring. It has also emphasized the importance of documenting vaccination history and clinical presentation.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of vaccine-associated poliomyelitis, improving data accuracy and public health monitoring. It has also emphasized the importance of documenting vaccination history and clinical presentation.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    CDC - Polio Vaccination

Coding & Billing References

  • •
    CDC - Polio Vaccination

Frequently Asked Questions

What is the difference between vaccine-associated poliomyelitis and wild poliovirus poliomyelitis?

Vaccine-associated poliomyelitis occurs due to the live attenuated virus in the OPV reverting to a neurovirulent form, while wild poliovirus poliomyelitis is caused by naturally occurring strains of the virus. Accurate coding requires knowledge of the patient's vaccination history.