Gammaherpesviral mononucleosis without complication
ICD-10 B27.00 is a billable code used to indicate a diagnosis of gammaherpesviral mononucleosis without complication.
Gammaherpesviral mononucleosis is primarily caused by the Epstein-Barr virus (EBV) or other gammaherpesviruses, leading to a clinical presentation similar to infectious mononucleosis. Patients typically present with symptoms such as fever, sore throat, lymphadenopathy, and fatigue. The diagnosis is often confirmed through serological testing, including heterophile antibody tests (e.g., Monospot test) and specific EBV antibody panels. In the absence of complications, the condition is generally self-limiting, with supportive care being the mainstay of treatment. Antiviral medications may be considered in severe cases or immunocompromised patients, although they are not routinely used for uncomplicated cases. The condition is characterized by the proliferation of atypical lymphocytes and can lead to splenomegaly. It is important to differentiate gammaherpesviral mononucleosis from other viral infections, such as cytomegalovirus (CMV) mononucleosis, which can present similarly but requires different management.
Detailed clinical history, laboratory test results, and treatment plans must be documented.
Patients presenting with fever, sore throat, and lymphadenopathy requiring differential diagnosis.
Consideration of immunocompromised status and potential complications.
Comprehensive patient history and physical examination findings, including symptom duration.
Initial evaluation of patients with symptoms suggestive of mononucleosis.
Monitoring for complications and ensuring follow-up care.
Used to confirm EBV infection in patients presenting with mononucleosis symptoms.
Document the reason for the test and the clinical findings leading to the suspicion of EBV.
Infectious disease specialists may require more detailed serological panels.
Common symptoms include fever, sore throat, swollen lymph nodes, and fatigue. Patients may also experience splenomegaly and atypical lymphocytes in their blood.