Gammaherpesviral mononucleosis with polyneuropathy
ICD-10 B27.01 is a billable code used to indicate a diagnosis of gammaherpesviral mononucleosis with polyneuropathy.
Gammaherpesviral mononucleosis is primarily caused by the Epstein-Barr virus (EBV) or other gammaherpesviruses, leading to a clinical presentation similar to infectious mononucleosis. Patients typically present with fever, sore throat, lymphadenopathy, and fatigue. In cases where polyneuropathy is present, patients may experience weakness, numbness, or tingling in the extremities due to the involvement of peripheral nerves. The pathophysiology involves the virus's ability to infect B lymphocytes, leading to an immune response that can inadvertently affect the nervous system. Diagnosis is often confirmed through serological tests for heterophile antibodies, EBV-specific antibodies, and sometimes PCR testing for viral DNA. Treatment primarily focuses on supportive care, as antiviral medications like acyclovir may be used in severe cases, although their efficacy in gammaherpesviral infections is limited. Monitoring for complications such as splenic rupture or neurological manifestations is crucial.
Detailed history of symptoms, laboratory test results, and treatment plans.
Patients presenting with mononucleosis-like symptoms and neurological complaints.
Ensure clear documentation of the viral etiology and any neurological assessments performed.
Neurological examination findings, diagnostic imaging results, and treatment responses.
Patients with polyneuropathy symptoms following a viral infection.
Document the timeline of neurological symptoms in relation to the viral infection.
Used to confirm EBV infection in patients presenting with mononucleosis symptoms.
Document the reason for the test and the results.
Infectious disease specialists should ensure comprehensive testing for viral infections.
Common symptoms include fever, sore throat, swollen lymph nodes, fatigue, and in some cases, neurological symptoms such as weakness or numbness.
Diagnosis is typically made through clinical evaluation, serological tests for EBV antibodies, and sometimes PCR testing for viral DNA.
Treatment is primarily supportive, but antiviral medications may be considered in severe cases. Management of polyneuropathy may involve physical therapy and symptomatic relief.
