Gammaherpesviral mononucleosis with meningitis
ICD-10 B27.02 is a billable code used to indicate a diagnosis of gammaherpesviral mononucleosis with meningitis.
Gammaherpesviral mononucleosis with meningitis is a viral infection characterized by the presence of the gammaherpesvirus, which includes Epstein-Barr virus (EBV) and human herpesvirus 6 (HHV-6). This condition typically presents with symptoms similar to infectious mononucleosis, such as fever, sore throat, lymphadenopathy, and fatigue. However, in cases where meningitis is present, patients may also exhibit neurological symptoms such as headache, neck stiffness, and altered mental status. Diagnosis is primarily made through serological testing for specific antibodies against the gammaherpesvirus, along with PCR testing to detect viral DNA in cerebrospinal fluid (CSF) when meningitis is suspected. Treatment usually involves supportive care, as antiviral medications may not be effective against gammaherpesviruses. In severe cases, particularly those involving neurological complications, antiviral therapy such as acyclovir may be considered. Monitoring for complications is crucial, as the condition can lead to significant morbidity if not managed appropriately.
Detailed clinical history, laboratory results, and treatment plans must be documented.
Patients presenting with fever, lymphadenopathy, and neurological symptoms.
Consideration of co-infections and the need for comprehensive testing.
Neurological examination findings, imaging results, and CSF analysis must be included.
Patients with altered mental status or severe headache alongside mononucleosis symptoms.
Documentation of neurological deficits and their progression is critical.
Used when viral meningitis is suspected.
Document the reason for testing and clinical findings.
Infectious disease specialists should ensure comprehensive testing.
Common symptoms include fever, sore throat, lymphadenopathy, fatigue, and in cases with meningitis, headache and neck stiffness.
Diagnosis is made through serological tests for antibodies and PCR testing of cerebrospinal fluid to detect viral DNA.
Treatment is primarily supportive, but antiviral medications like acyclovir may be considered in severe cases.