Other infectious mononucleosis without complication
ICD-10 B27.80 is a billable code used to indicate a diagnosis of other infectious mononucleosis without complication.
Infectious mononucleosis is primarily caused by the Epstein-Barr virus (EBV), but can also be associated with other viral infections such as cytomegalovirus (CMV) and human immunodeficiency virus (HIV). This condition is characterized by fever, sore throat, lymphadenopathy, and fatigue. The diagnosis is typically made through clinical evaluation and confirmed with laboratory tests, including heterophile antibody tests (e.g., Monospot test) and specific serological tests for EBV and CMV. Other viral infections that may present similarly include toxoplasmosis and certain viral hepatitis infections. Treatment is generally supportive, focusing on symptom relief, as antiviral medications are not routinely indicated for EBV-related mononucleosis. However, in cases where CMV is the causative agent, antiviral therapy may be considered. The absence of complications such as splenic rupture or secondary infections is a key aspect of this diagnosis, making it essential for coders to accurately document the clinical scenario and any relevant laboratory findings.
Thorough clinical notes detailing symptoms, laboratory results, and follow-up care.
Patients presenting with fatigue, sore throat, and lymphadenopathy.
Ensure documentation reflects the absence of complications and any differential diagnoses considered.
Detailed serological test results and clinical evaluations.
Patients with atypical presentations or those requiring antiviral therapy.
Document any additional viral testing performed and rationale for treatment decisions.
When testing for EBV in suspected cases of mononucleosis.
Document the reason for the test and the clinical findings.
Infectious disease specialists may require more detailed serological profiles.
The most common cause is the Epstein-Barr virus (EBV), but other viruses such as cytomegalovirus (CMV) and HIV can also cause mononucleosis-like symptoms.
