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v1.0.0
ICD-10 Guide
ICD-10 CodesB34.2

B34.2

Herpesviral encephalitis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B34.2 is a billable code used to indicate a diagnosis of herpesviral encephalitis.

Key Diagnostic Point:

Herpesviral encephalitis is a severe neurological condition primarily caused by the herpes simplex virus (HSV), most commonly HSV-1, though HSV-2 can also be implicated. This condition is characterized by inflammation of the brain, leading to symptoms such as fever, headache, seizures, altered mental status, and focal neurological deficits. Diagnosis typically involves a combination of clinical evaluation, imaging studies like MRI, and laboratory tests including PCR (polymerase chain reaction) assays of cerebrospinal fluid (CSF) to detect viral DNA. Prompt diagnosis and treatment are critical, as herpesviral encephalitis can lead to significant morbidity and mortality if not addressed swiftly. Antiviral therapy, primarily with acyclovir, is the cornerstone of treatment and is most effective when initiated early in the course of the disease. Long-term outcomes can vary, with some patients experiencing persistent neurological deficits.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiation between HSV-1 and HSV-2 infections
  • Need for precise documentation of clinical symptoms
  • Variability in diagnostic methods and results
  • Potential for co-infections or other encephalitis causes

Audit Risk Factors

  • Inadequate documentation of clinical findings
  • Failure to specify the type of herpes virus
  • Misclassification of encephalitis type
  • Lack of supporting lab results for diagnosis

Specialty Focus

Medical Specialties

Neurology

Documentation Requirements

Detailed neurological examination findings, imaging results, and lab test outcomes.

Common Clinical Scenarios

Patients presenting with acute onset of seizures, altered mental status, or focal neurological deficits.

Billing Considerations

Ensure clear documentation of the patient's history and symptom progression to support the diagnosis.

Infectious Disease

Documentation Requirements

Laboratory confirmation of herpes virus, treatment response, and any co-morbid infections.

Common Clinical Scenarios

Patients with suspected viral encephalitis requiring antiviral therapy.

Billing Considerations

Document the rationale for antiviral therapy and any complications that arise during treatment.

Coding Guidelines

Inclusion Criteria

Use B34.2 When
  • According to ICD
  • 10 guidelines, B34
  • 2 should be used when herpesviral encephalitis is confirmed through clinical and laboratory findings
  • It is important to document the specific type of herpes virus when applicable

Exclusion Criteria

Do NOT use B34.2 When
No specific exclusions found.

Related CPT Codes

87491CPT Code

Herpes Simplex Virus (HSV) PCR

Clinical Scenario

Used to confirm diagnosis in patients presenting with encephalitis symptoms.

Documentation Requirements

Document the reason for testing and the clinical symptoms leading to the test.

Specialty Considerations

Neurologists and infectious disease specialists should ensure that the rationale for testing is clearly documented.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of herpesviral encephalitis, improving the accuracy of data collection and reimbursement processes. It emphasizes the importance of detailed documentation and specificity in coding.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of herpesviral encephalitis, improving the accuracy of data collection and reimbursement processes. It emphasizes the importance of detailed documentation and specificity in coding.

Reimbursement & Billing Impact

reimbursement processes. It emphasizes the importance of detailed documentation and specificity in coding.

Resources

Clinical References

  • •
    CDC - Herpes Simplex Virus

Coding & Billing References

  • •
    CDC - Herpes Simplex Virus

Frequently Asked Questions

What are the common symptoms of herpesviral encephalitis?

Common symptoms include fever, headache, seizures, confusion, and focal neurological deficits. Rapid onset of these symptoms is typical.

How is herpesviral encephalitis diagnosed?

Diagnosis is primarily through PCR testing of cerebrospinal fluid, along with clinical evaluation and imaging studies.

What is the primary treatment for herpesviral encephalitis?

The primary treatment is antiviral therapy, most commonly with acyclovir, which is most effective when started early.